TITLE:
Effect of Different Parts of Kigelia africana Fruit Aqueous Extracts on Sperm Parameters and Testis
AUTHORS:
Maïmouna Coura Koné, Blaise Wokapeu Kpan, Ibrahima Kandé, Roger Koffi Kouakou, Romuald Sylvère Koman, Yao Konan, Koffi Kouakou
KEYWORDS:
Kigelia, Spermatogenesis, Density, Mobility, Testis
JOURNAL NAME:
Advances in Reproductive Sciences,
Vol.9 No.3,
August
30,
2021
ABSTRACT: Kigelia africanais a plant of ivoirian pharmocopae commonly usedin infertility treatment. The Kigelia africanawhole fruit extractsare knownto improve sperm parameters like density, morphologie and mobility. However, data related to efficiency of different parts of the fruit are lack. The aim of this study was to know the effects of aqueous extracts of the whole Kigelia africana fruit (AP) and of the fruit without the peel (SP) on the sperm parameters and testicular tissue of mice. The phytochemical composition analysis of the SP and AP aqueous extracts of Kigelia africana fruit reveals several secondary metabolites in variable abundance. The sperm densities (Figure 1) of the SP (~78.106 spz/ml ± 2.60) and AP (~96.15×106 spz/ml ± 2.44) groups were higher than that of the control (~63.95.106 spz/ml ± 2.93) with a highly significant difference (p Figure 2). However, the percentage of motile spermatozoa was much higher in SP group (~76% ± 5.48%), at least twice as high compared to the control and AP group with a highly significant difference (p spreserve the gonad and enhance spermatogenesis. All together, our data revealed that AP and SP aqueous extractsof Kigelia africana stimulated spermatogenesis, sperm mobility and didn’t affect the gonads.There is however a difference in the effects of the two extracts with better efficacy of AP extractsfor increasing sperm number while SP more significantly improves sperm mobility and morphology.