Synthesis of Biphasic Calcium Phosphate by Hydrothermal Route and Conversion to Porous Sintered Scaffold

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Journal of Biomaterials and Nanobiotechn... > Vol.4 No.3, July 2013

Synthesis of Biphasic Calcium Phosphate by Hydrothermal Route and Conversion to Porous Sintered Scaffold ()

Sunarso , Ahmad Fauzi Mohd Noor, Shah Rizal Kasim, Radzali Othman, Ika Dewi Ana, Kunio Ishikawa

Department of Biomaterials, Faculty of Dental Science, Kyushu University, Fukuoka, Japan..
Department of Biomedical Sciences and Technology, Faculty of Dentistry, Universitas Gadjah Mada, Yogyakarta, Indonesia;.
School of Materials and Mineral Resources Engineering, Universiti Sains Malaysia, Penang, Malaysia;.

DOI: 10.4236/jbnb.2013.43034 PDF HTML 3,491 Downloads 5,068 Views Citations

Abstract

Biphasic calcium phosphate (BCP) consisting of hydroxyapatite (HA) and β-tricalcium phosphate (β-TCP) was successfully synthesized by new hydrothermal route using β-TCP as precursor. The X-ray diffraction analysis of as-synthesized powder indicated that β-TCP had been transformed into HA phase and amount of HA formed gradually increased with prolonged time. The results revealed that the recent technique may be able to control the composition of the obtained BCP which would influence the bioresorbability. Porous body of BCP was prepared by impregnation of polymeric sponge template with the slurry of the powder followed by sintering. The X-ray diffraction of porous product revealed that the composition of β-TCP increased after sintering indicating that HA had been decomposed. Porous BCP obtained from the recent technique possessed both macro and micropores structure which are useful for rapid tissue formation. Besides, the recent porous fabrication technique yielded porous BCP which preserved the sponge template morphology, enabling it to fabricate porous material with controlled pores structure.

Keywords

Biphasic; Calcium Phosphate; β-TCP; Hydroxyapatite; Hydrothermal; Porous

Share and Cite:

S. , A. Noor, S. Kasim, R. Othman, I. Ana and K. Ishikawa, "Synthesis of Biphasic Calcium Phosphate by Hydrothermal Route and Conversion to Porous Sintered Scaffold," Journal of Biomaterials and Nanobiotechnology, Vol. 4 No. 3, 2013, pp. 273-278. doi: 10.4236/jbnb.2013.43034.

Conflicts of Interest

The authors declare no conflicts of interest.

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