Author(s)

Jasminka Giacometti, Alena Buretic Tomljanovic, Cedomila Milin, Mira Cuk, Biserka Radosevic Stasic

Department of Biology and Medical Genetics, Medical Faculty University of Rijeka, Rijeka, Croatia.
Department of Biotechnology, University of Rijeka, Rijeka, Croatia.
Department of Chemistry and Biochemistry, Medical Faculty University of Rijeka, Rijeka, Croatia.
Department of Physiology, Immunology and Pathophysiology, Medical Faculty University of Rijeka, Rijeka, Croatia..

We examined the effect of dietary fats on the kinetics of liver regeneration after one-third partial hepatectomy (PH) in male Balb/c mice. Corn and olive supplemented diets were chosen as a model of n-6 and n-9 diets. Phospholipid fatty acids were determined by gas chromatography (GC) after previous fractionation by solid-phase extraction using aminopropyl (NH2) column, and data were analysed by nonparametric Kruskal-Wallis test. Diet enriched with corn and olive oil did not affect the balance of lipid disorders during liver regeneration after 1/3 PH. Desaturases activity direction has changed depending on the used diet. The key role in the alteration of the polar fatty acids profile at all stages of liver regeneration and examined dietary fats is played by activity of stearoyl-CoA desaturase (SCD).

Fatty Acids; Phospholipids; One-Thirds Partial Hepatectomy; Olive Oil; Corn Oil; Diet

J. Giacometti, A. Tomljanovic, C. Milin, M. Cuk and B. Stasic, "Olive and Corn Oil Enriched Diets Changed the Phospholipid Fatty Acid Composition in Mice Liver after One-Thirds Hepatectomy," Food and Nutrition Sciences, Vol. 3 No. 2, 2012, pp. 240-248. doi: 10.4236/fns.2012.32035.