A Multi-Center International Survey Related to the Nutritional Support after Hematopoietic Stem Cell Transplantation Endorsed by the ASIA Pacific Blood and Marrow Transplantation (APBMT)
Shigeo Fuji, Takehiko Mori, Vincent Lee, Jessica Cheng, Natalie Linton, Albert Lie, Navin Khattry, Akio Shigematsu, Naoyuki Uchida, Tetsuya Eto, Nguyen Duy Thang, Yi-Chang Liu, Deok-Hwan Yang, Jin Seok Kim, Joon Ho Moon, Dae-Young Kim, Minako Iida, Ritsuro Suzuki, Yoshihisa Kodera, Sung-Won Kim
Department of Hematology and Hematopoietic Stem Cell Transplantation, National Cancer Center Hospital, Tokyo, Japan..
Department of Hematology and Oncology, Chonnam National University Hwasun Hospital, Jeollanam-do, Korea;.
Department of Hematology and Oncology, Hokkaido University Hospital, Hokkaido, Japan;.
Department of Hematology and Oncology, Kaohsiung Medical University Hospital, Taiwan (China);.
Department of Hematology and Oncology, Kyungpook National University Hospital, Daegu, Korea (South);.
Department of Hematology, Asan Medical Center, Seoul, Korea (South);.
Department of Hematology, Hamanomachi Hospital, Fukuoka, Japan;.
Department of Hematology, Toranomon Hospital, Tokyo, Japan;.
Department of Hematology, University Hospital Wuerzburg, Wuerzburg, Germany;.
Department of HSCT Data Management and Biostatistics, School of Medicine, Nagoya University, Nagoya, Japan;.
Department of Medical Oncology, Tata Memorial Center, Mumbai, India;.
Department of Medicine, Queen Mary Hospital, Hong Kong (China);.
Department of Nutrion Services, St Vincent’s Hospital Sydney, Sydney, Australia;.
Department of Pediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong (China);.
Department of Promotion for Blood and Marrow Transplantation, School of Medicine, Aichi Medical University, Nagakute, Japan;.
Division of Hematology, Keio University Hos- pital, Tokyo, Japan;.
Division of Hematology, Yonsei University College of Medicine, Severance Hospital, Seoul, Korea (South);.
Hue Regional Hematology and Blood Transfusion Center, Hue Central Hospital, Hue City, Vietnam;.
DOI: 10.4236/fns.2012.33060   PDF   HTML     5,072 Downloads   7,813 Views   Citations


Background: The nutritional support after hematopoietic stem cell transplantation (HSCT) has not been well established due to the scarcity of clinical trials. To conduct international clinical trials in Asia, we performed the questionnaire survey to investigate the current standard of nutritional support after HSCT. Method: We sent the questionnaire to the physicians nominated by the Asia Pacific Blood and Marrow Transplantation (APBMT) members of each country/ region. Result: We received 15 responses from 7 different countries/regions. The target calorie amount is 1.0 - 1.3 × basal energy expenditure (BEE) in 11 institutes when partial parenteral nutrition is used. When total parenteral nutrition (TPN) is used, the target calorie amount is 1.0 - 1.3 × BEE in 9 institutes and 1.3 - 1.5 × BEE in 4 institutes. Lipid emulsion is routinely used in 12 institutes. Multivitamins and trace elements are routinely added to TPN used in most institutes. It is still uncommon to use the immunonutrition. Blood glucose levels are routinely monitored in all institutes, but the target range varies (<110 in 2 institutes, <150 in 4 institutes, and <200 in 8 institutes). Conclusions: Basic nutritional support is similar in participating institutes. However, the target glucose level varies and the use of immunonutrition is rather rare. These points can be the theme of future clinical trials.

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S. Fuji, T. Mori, V. Lee, J. Cheng, N. Linton, A. Lie, N. Khattry, A. Shigematsu, N. Uchida, T. Eto, N. Thang, Y. Liu, D. Yang, J. Kim, J. Moon, D. Kim, M. Iida, R. Suzuki, Y. Kodera and S. Kim, "A Multi-Center International Survey Related to the Nutritional Support after Hematopoietic Stem Cell Transplantation Endorsed by the ASIA Pacific Blood and Marrow Transplantation (APBMT)," Food and Nutrition Sciences, Vol. 3 No. 3, 2012, pp. 417-421. doi: 10.4236/fns.2012.33060.

Conflicts of Interest

The authors declare no conflicts of interest.


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