TITLE:
Effects of Yerba Mate Consumption (Ilex paraguariensis) on Cardiac Remodeling in Rats
AUTHORS:
Carlos Eduardo Brochini de Paiva, Thaíssa Baptista Brochini de Paiva, Isabelle Tiburcio Pecin Ferreira, Sandra Cristina Genaro, Danilo Silva Martins Santos, Thaoan Bruno Mariano, Robson Chacon Castoldi, Rafael Stuani Floriano, Julia Amanda Rodrigues Fracasso, Lucas Pires Guarnier, Marina Politi Okoshi, Francis Lopes Pacagnelli
KEYWORDS:
Tereré, Ilex paraguariensis, Yerba Mate, Cardiac Remodeling, Fractal Dimension, Hypertrophy
JOURNAL NAME:
Food and Nutrition Sciences,
Vol.15 No.8,
August
30,
2024
ABSTRACT: This study investigated the effects of yerba mate consumption, a South American beverage, on cardiac remodeling in rats. For this purpose, 24 male Wistar rats were divided into Control Group (CG) which received filtered water and a standard diet, and Yerba Mate Group (YM), 6 g of Ilex paraguariensis in 100 ml water and the same diet, for 30 days. The YM group showed a reduction in final body weight and food consumption without altering weight gain. Regarding cardiac remodeling, the YM group exhibited a decrease in the right ventricle weight/final body weight ratio, suggesting cardiac atrophy, without affecting the atria and left ventricle. There was no change in cardiomyocyte area or nuclear fractal dimension in both groups. However, animals that consumed yerba mate showed increased collagen deposition and a smaller fractal dimension in the left ventricle. The consumption of yerba mate at room temperature for 30 days induced changes in cardiac remodeling, as evidenced by increased collagen deposition and alterations in fractal dimension in the left ventricle.