Article citationsMore>>
Fujioka, N., Hibino, S., Wakahara, A., Kawagishi, T., Taku, K., Mizuno, S., Watanabe, S., Takahashi, H., Hamada, U., Takahashi, Y. and Yonei, Y. (2009) Effects of various soap elements on skin. Anti-Aging Medicine, 6, 109-118. http://dx.doi.org/10.3793/jaam.6.109
has been cited by the following article:
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TITLE:
Tolerability and hydrating effects of an anti-aging gynaecological collagen cream in women in menopause
AUTHORS:
Andrea F. D. Di Stefano, Milko M. Radicioni, Andrea Vele, Anna Mancarella Eberhardt, Giorgio Caccia, Francesca Focanti, Enrica Salvatori
KEYWORDS:
Skin Hydration; Vaginal Moisturiser; Skin Viscoelasticity; Corneometer; Cutometer; Perineum
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.4 No.3,
February
21,
2014
ABSTRACT:
Background and Aims: A
gynaecological cream containing collagen, phytocollagen, hyaluronate and vitamins
was investigated in women in menopause. Methods: The cream was daily applied to
the vaginal mucosa and the perineal skin as well as to the abdominal skin
(healthy skin used as control) for 1 week and then on alternate days for other
2 weeks. Skin hydration and viscoelasticity were measured at baseline and after
8 and 21 days by Corneometer? CM 825
and Cutometer? MPA 850, respectively. The product use comfort
and the moisturising of the vaginal mucosa were evaluated by the volunteers
through a questionnaire and a visual analogue scale, respectively. Results: The
local tolerability was excellent for nearly all of the volunteers (90% - 95%)
and according both to dermatologist’s and
gynaecologist’s evaluation. Related
adverse reactions had a frequency of 15% (10% vulvovaginal burning
sensation and 5% vulvovaginal discomfort).
The topical hydration increased both in the perineal and the abdominal skin. Hydration increase vs. baseline was more marked
on day 8 than on day 21 and was significant in the abdominal skin (p-value
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