TITLE:
Comparative study between the effect of Momordica charantia (wild and hybrid variety) on hypoglycemic and hypolipidemic activity of alloxan induced type 2 diabetic long-evans rats
AUTHORS:
Subbroto Kumar Saha, Md. Ezazul Haque, Dipa Islam, Md. Matiar Rahman, Md. Rezuanul Islam, Anzana Parvin, Shahedur Rahman
KEYWORDS:
Type 2 Diabetes Mellitus; Momordica Charantia; Alloxan, Hypoglycemic Effect; Hypolipidemic Effect; Glibenclamide
JOURNAL NAME:
Journal of Diabetes Mellitus,
Vol.2 No.1,
February
22,
2012
ABSTRACT: This study was undertaken to evaluate the hypoglycemic and hypolipidemic effect of Momordica charantia (wild and hybrid variety) powder on alloxan induced type 2 diabetic male Long-Evans rats. Oral feeding of the M. charantia powder slightly decreased serum total cholesterol, triglyceride levels and LDL-cholesterol compared with wild, hybrid and standard drug. M. charantia wild variety showed more significant (p M. charantia did not show any significant effect on HDL-cholesterol and liver glycogen. Thus, results of the study prove that the wild variety of M. charantia fruit have potent antidiabetic and antilipidemic property.