TITLE:
Biochemical Changes in the Brain and Metabolism as Risk Factors of Neurological Disorders
AUTHORS:
Kevin Patrick Barman
KEYWORDS:
Dietary Health, Magnesium Intake, Metabolic Syndrome, Monoamine Hypothesis, Neurological Disorders, Oxytocin Receptor
JOURNAL NAME:
World Journal of Neuroscience,
Vol.12 No.2,
May
6,
2022
ABSTRACT: This paper aims to examine theories that attempt to
explain biochemical changes in the brain as well as the metabolism of
individuals who experience symptoms and conditions related to neurological
disorders like depression. A systematic literature search was performed on NCBI
and PubMed. The search included the keywords neurological disorders, monoamine
hypothesis, metabolic syndrome, oxytocin receptor, dietary health, and
magnesium intake. Twenty-five research articles met the criteria for the
literature review of this examination. In particular, this paper will review
multiple studies that investigate the monoamine (MAO) hypothesis of depression
and metabolic syndrome (MetS) as a risk factor for neurological disorders. While studies that
evaluate additional risk factors for neurological disorders, such as autoimmunity and
rheumatic diseases, oxytocin receptor (OXTR) DNA methylation in postpartum
depression, dietary health in children and their psychological health, and
dietary magnesium and cardiovascular disease, will be reviewed as well.