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https://doi.org/10.1016/j.jconrel.2014.04.018

has been cited by the following article:

• TITLE: Electrospun PLLA Membranes for Caffeine Delivery: Diffusional Approach

  AUTHORS: Ana Paula S. Immich, José Antonio Tornero, Francesc Cano Casas, Manuel J. Lis Arias

  KEYWORDS: Diffusion, Polymer, Nano Escale, Kinetics

  JOURNAL NAME: Journal of Biomedical Science and Engineering, Vol.10 No.12, December 29, 2017

  ABSTRACT: One of the great advantages of electrospun fibers is the large tridimensional area produced, capable of storing any type of material. The aim of our investigation is to study the electrospinning technique to produce polymer membranes for drug delivery applications, given their large surface area and ability to transport a bioactive compound. A mathematical modeling of the delivery system kinetics was also studied to find the mechanism that controls the releasing process. Results showed that electrospinning could provide regular and smooth membranes suitable for drug delivery processes. The mathematical modeling also proved that thicker PLLA membranes exhibited a Fickian diffusion behavior during the drug transport, presenting better control in drug delivery processes.