Abu-Shanab, F.A., Redhouse, A.D., Thompson, J.R. and Wakefield, B.J. (1995) Synthesis of 2,3,5,6-Tetrasubstituted Pyridines from Enamines Derived from N,N-Dimethylformamide Dimethyl Acetal. Synthesis, 5, 557-560.
http://dx.doi.org/10.1055/s-1995-3954

has been cited by the following article:

• TITLE: Preparation of Polyfunctionally Substituted Pyridine-2(1H)-Thione Derivatives as Precursors to Bicycles and Polycycles

  AUTHORS: Fathi A. Abu-Shanab, Sayed A. S. Mousa, Sherif M. Sherif, Mohamed I. Hassan

  KEYWORDS: Acetyl Acetone, DMFDMA, Malononitrile Dimmer, Bipyridyl, 5-Acetylpyridinethione

  JOURNAL NAME: International Journal of Organic Chemistry, Vol.4 No.5, December 31, 2014

  ABSTRACT: Reaction of acetylacetone with 1 mole of dimethylformamide dimethyl acetal (DMFDMA) affords enamine 2a which reacts with cyanothioacetamide to give pyridinethione 3a. Pyridinethione 3a reacts with methyl iodide, halogenated compounds, aromatic aldehyde and malononitrile/elemental sulfur to yiled compounds 7-10 respectively. Reactions of thioether 7 in ethanolic K2CO3, 1 mole DMFDMA and 4-(dimethylamino)benzaldehyde give compounds 11, 13, 14 respectively. Enaminone 12 can be prepared by reaction of compound 11 with DMFDMA. We have demonstrated some reactions in order to show the potential usefulness of the prepared compounds for the preparation of new bipyridyl compounds 15, 16, 18, bicyclic compounds 17 and uncommon tricyclic compounds 20, 21, 22 and 23 respectively using DMFDMA.