TITLE:
Observation of Atherosclerotic Plaque Phantoms through Saline or Blood Layers by Near-Infrared Hyperspectral Imaging
AUTHORS:
Katsunori Ishii, Akiko Kitayabu, Ryo Nagao, Kunio Awazu
KEYWORDS:
Hyperspectral Imaging, Near-Infrared Range, Atherosclerotic Plaque, Angioscopy
JOURNAL NAME:
Optics and Photonics Journal,
Vol.4 No.10,
October
13,
2014
ABSTRACT: We observed
atherosclerotic plaque phantoms using a novel near-infrared (NIR) hyperspectral
imaging (HSI) technique. Data were obtained through saline or blood layers to
simulate an angioscopic environment for the phantom. For the study, we
developed a NIR-HSI system with an NIR supercontinuum light source and mercury-cadmium-telluride
camera. Apparent spectral absorbance was obtained at wavelengths of 1150 - 2400
nm. Hyperspectral images of lipid were constructed using a spectral angle
mapper algorithm. Bovine fat covered with saline or blood was observed using
hyperspectral images at a wavelength around 1200 nm. Our results show that
NIR-HSI is a promising angioscopic technique with the potential to identify
lipid-rich plaques without clamping and saline injection.