Leon, I. E., Porro, V., Di, V.A.L., Naso, L.G., Williams, P.A.M., Bollati-Fogolin, M. and Etcheverry, S.B. (2014) Antiproliferative and Apoptosis-Inducing Activity of an Oxidovanadium(IV) Complex with the Flavonoid Silibinin against Osteosarcoma Cells. Journal of Biological Inorganic Chemistry, 19, 59-74.
http://dx.doi.org/10.1007/s00775-013-1061-x

has been cited by the following article:

• TITLE: Photocleavage Properties and DNA-Binding Studies of Oxovanadium Complexes Incorporating 2-(2-Hydroxybenzylideneamino) Isoindoline-1,3-Dione and Fluoro-Phenanthroline Derivatives

  AUTHORS: Peng Ying, Pengfei Zeng, Jiazheng Lu, Ning Yang, Hongyuan Chen

  KEYWORDS: Oxovanadium Complexes, Synthesis, DNA-Binding, Photocleavage

  JOURNAL NAME: Open Journal of Inorganic Chemistry, Vol.4 No.4, September 23, 2014

  ABSTRACT: Three mononuclear oxovanadium complexes [VO(Hbid)(CF3PIP)] (1) (Hbid=(E)-2-(2-hydroxybenzylideneamino) isoindoline-1,3-dione, CF3PIP=2-(2-trifluoromethyl phenyl)imidazole[4,5-f][1,10] phenanthroline), [VO(Hbid)(m-CF3PIP)]; (2) (m-CF3PIP=2-(3-trifluoromethyl phenyl)imidazole [4, 5-f][1,10]phenanthroline) and [VO(Hbid)(p-CF3PIP)]; (3) (p-CF3PIP=2-(4-trifluoromethyl phenyl) imidazole[4,5-f][1,10]phenanthroline) have been synthesized and characterized by elemental analysis, IR, molar conductance, ES-MS and 1H NMR. The DNA-binding properties of these complexes were studied by using UV-Vis absorption titration, fluorescence spectra, viscosity measurements and thermal denaturation studies. The results show that 1, 2 and 3 interact with calf thymus DNA (CT-DNA) by intercalation modes and the magnitude of their intrinsic binding constants (Kb values) follows the order: 2