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Chan, C.Y.J. and Moore, R. (2008) Sickle Cell. In: DiPiro, J.T., Talbert, R.L., Yee, G., Matzke, G., Wells, B. and Posey, L.M., Eds., Pharmacotherapy—A Pathophysiologic Approach, 7th Edition, McGraw-Hill, New York, 1686-1687.

has been cited by the following article:

  • TITLE: Sickle Cell Gene Transmission: Do Public Servants in Tamale, Ghana Have the Right Knowledge and Attitude to Curb It?

    AUTHORS: Evans Paul Kwame Ameade, Baba Sulemana Mohammed, Gideon Kofi Helegbe, Sualisu Yakubu

    KEYWORDS: Sickle Cell Disease, Public Servants, Knowledge, Attitude, Tamale

    JOURNAL NAME: Open Journal of Preventive Medicine, Vol.5 No.6, June 30, 2015

    ABSTRACT: Introduction: Sickle cell disease (SCD) is exerting enormous public health and economic burden on many countries. To reduce these effects, the World Health Organization is urging countries, especially those in Africa, to increase public awareness of this disease. This study accessed whether public servants in Tamale, Ghana possess adequate knowledge and positive attitude towards SCD. Method: A total of 320 public servants within the Tamale Metropolis were invited to complete a questionnaire in a cross-sectional study. Data were analyzed using GraphPad 5.01. Association between different variables was tested. Results: The media was the main source of information for a majority of the 94.2% of respondents who had ever heard of SCD. Knowledge of respondents on transmission and testing of SCD was above 70% but they recorded less than 40% in SCD’s incurability, prevalence, effect of SCD on life span and pregnancy. The mean knowledge score of respondents was (11.1 ± 5.11)/22 or 50.7%. Only about a quarter knew their sickling status or that of their spouses before marriage or first child. Although 78.0% of respondents would call off marriages if they became aware of genetic incompatibility, the overall mean attitude, (2.857 ± 1.97)/ 7.0% or 40.8% was poor. There was a positive and significant correlation between the knowledge of respondents and their attitude towards SCD (r = 0.494, p