Sickle Cell Gene Transmission: Do Public Servants in Tamale, Ghana Have the Right Knowledge and Attitude to Curb It?


Introduction: Sickle cell disease (SCD) is exerting enormous public health and economic burden on many countries. To reduce these effects, the World Health Organization is urging countries, especially those in Africa, to increase public awareness of this disease. This study accessed whether public servants in Tamale, Ghana possess adequate knowledge and positive attitude towards SCD. Method: A total of 320 public servants within the Tamale Metropolis were invited to complete a questionnaire in a cross-sectional study. Data were analyzed using GraphPad 5.01. Association between different variables was tested. Results: The media was the main source of information for a majority of the 94.2% of respondents who had ever heard of SCD. Knowledge of respondents on transmission and testing of SCD was above 70% but they recorded less than 40% in SCD’s incurability, prevalence, effect of SCD on life span and pregnancy. The mean knowledge score of respondents was (11.1 ± 5.11)/22 or 50.7%. Only about a quarter knew their sickling status or that of their spouses before marriage or first child. Although 78.0% of respondents would call off marriages if they became aware of genetic incompatibility, the overall mean attitude, (2.857 ± 1.97)/ 7.0% or 40.8% was poor. There was a positive and significant correlation between the knowledge of respondents and their attitude towards SCD (r = 0.494, p < 0.0001) hence respondents working in the health sector and those with tertiary level education had better attitudes towards SCD. Conclusion: Public servants in Ghana have moderate knowledge of SCD but their attitude towards the disease was poor. Public servants least considered genetic incompatibility before entering conjugal relationships. This poor attitude means the campaign for the reduction of sickle cell gene transmission must be intensified. Governments need to increase their investment on educational campaigns aimed at changing attitude of persons through provision of more knowledge about SCD.

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Kwame Ameade, E. , Mohammed, B. , Kofi Helegbe, G. and Yakubu, S. (2015) Sickle Cell Gene Transmission: Do Public Servants in Tamale, Ghana Have the Right Knowledge and Attitude to Curb It?. Open Journal of Preventive Medicine, 5, 299-308. doi: 10.4236/ojpm.2015.56033.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] Zdanovicz, M.M. (2003) Essentials of Pathophysiology for Pharmacy. CRC Press, New York, 34-35.
[2] Chan, C.Y.J. and Moore, R. (2008) Sickle Cell. In: DiPiro, J.T., Talbert, R.L., Yee, G., Matzke, G., Wells, B. and Posey, L.M., Eds., Pharmacotherapy—A Pathophysiologic Approach, 7th Edition, McGraw-Hill, New York, 1686-1687.
[3] Afolayan, J.A. and Jolayemi, F.T. (2011) Parental Attitude to Children with Sickle Cell Disease in Selected Health Facilities in Irepodun Local Government, Kwara State, Nigeria. Ethno-Medicine, 5, 30-40.
[4] Eboh, W. and Van den Akker, O.A. (1994) Antenatal Care of Women with Sickle Cell Disease. British Journal of Midwifery, 2, 6-11.
[5] World Health Organization (2010) Sickle Cell Disease: A Strategy for the WHO African Region. AFR/RC60/8. WHO, Malabo.
[6] Ohene-Frempong, K., Oduro, J., Tetteh, H., and Nkrumah, F. (2008) Screening Newborns for Sickle Cell Disease in Ghana. Pediatrics, 121, S120-S121.
[7] Adeyemo, O.A., Omidiji, O.O. and Shabi, O.A. (2007) Level of Awareness of Genetic Counselling in Lagos, Nigeria: Its Advocacy on the Inheritance of SCD. African Journal of Biotechnology, 6, 2758-2765.
[8] Konotey-Ahulu, F.I.D. (2011) Sickle Cell Trait Misinformation and Disinformation.
[9] Edwin, A.K., Edwin, F. and Etwire, V. (2011) Controlling Sickle Cell Disease in Ghana—Ethics and Option. Pan African Medical Journal, 10, 14.
[10] Ghana Districts (2012) A Repository of All Districts in the Republic of Ghana.
[11] Ajzen, I. (2002) Perceived Behavioral Control, Self-Efficacy, Locus of Control, and the Theory of Planned Behavior. Journal of Applied Social Psychology, 32, 665-683.
[12] Ohaeri, J.U., and Shokunbi, W.A. (2001) Attitudes and Beliefs of Relatives of Patients with Sickle Cell Disease. East African Medical Journal, 78, 174-179.
[13] Anie, K.A., Egunjobi, F.E. and Akinyanju, O.O. (2010) Psychosocial Impact of Sickle Cell Disorder: Perspectives from a Nigerian Setting. Globalization and Health, 6, 2.
[14] Al-Farsi, O.A., Al-Farsi, Y.M., Gupta, I., Ouhtit, A., Al-Farsi, A.K. and Al-Adawi, S. (2014) A Study on Knowledge, Attitude, and Practice towards Premarital Carrier Screening among Adults Attending Primary Healthcare Centers in a Region in Oman. BMC Public Health, 14, 380.
[15] Ibrahim, N.K.R., Al-Bar, H., Al-Fakeeh, A., Al Ahmadi, J., Qdi, M., Al-Bar, A. and Milaat, W. (2011) An Educational Program about Premarital Screening for Unmarried Female Student in King Abdul-Aziz University, Jeddah. Journal of Infection and Public Health, 4, 30-40.
[16] Abioye-Kuteyi, E.A., Oyegbade, O., Bello, I. and Osakwe, C. (2009) Sickle Cell Knowledge, Premarital Screening and Marital Decisions among Local Government Workers in Lle-Lfe, Nigeria. African Journal of Primary Health Care & Family Medicine, 1, 53-57.
[17] Olatona, F.A., Odeyemi, K.A., Onajole, A.T. and Asuzu, M.C. (2012) Effects of Health Education on Knowledge Ad Attitude of Youth Corps Members to Sickle Cell Disease and Its Screening in Lagos State. Journal of Community Medicine & Health Education, 2, 163.
[18] Osbourne, C.J. (2011) Sickle Cell Disease Awareness among College Students. MSc Thesis, University of Illinois at Urbana-Champaign, Urbana.
[19] Millan, J., Van Teijlingen, E. and Eboh, W. (2006) Knowledge and Attitudes towards Sickle Cell Disease Screening: A Study of Members of the UK Sickle Cell Society. Robert Gordon University, Aberdeen, 38-49.
[20] Long, K.A., Thomas, S.B., Grubs, R.E., Gettig, E.A., and Krishnamurti, L. (2011) Attitudes and Beliefs of African-American towards Genetics, Genetic Testing, and Sickle Cell Disease Education and Awareness. Journal of Genetic Counseling, 20, 572-592.
[21] Oludare, G.O. and Ogili, M. (2013) Knowledge, Attitude and Practice of Premarital Counseling for Sickle Cell Disease among Youth in Yaba, Nigeria. African Journal of Reproductive Health, 17, 175-182.
[22] Al-Kindi, R., Al-Rujaibi, A. and Al-Kendi, M. (2012) Knowledge and Attitude of University Students towards Premarital Screening Program. Oman Medical Journal, 27, 291-296.
[23] Gil, K.M., Abrams, M.R., Phillips, G. and Keefe, F.J. (1989) Sickle Cell Disease Pain: Relation of Coping Strategies to Adjustment. Journal of Consulting and Clinical Psychology, 57, 725-731.
[24] Al-Aama, J.Y. (2010) Attitudes towards Mandatory National Premarital Screening for Hereditary Hemolytic Disorders. Health Policy, 97, 32-37.

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