The Q-Switched Nd: YAG Laser in Tattoo Removal and the Effect of Lymphatic Elimination: An Experimental Study in Rabbits
S. Irkoren, C. Demirdover, B. Z. Akad, M. Gorgu
DOI: 10.4236/ss.2011.25058   PDF    HTML     7,134 Downloads   14,203 Views   Citations

Abstract

Background: Previously described methods for removal of tattoos are chemical, mechanical, surgical, termal and laser assited methods. Invention of the Q-switch mode, advanced the laser method, to be one of the most effective methods of tattoo removal. Objective: Comparing the tattoo removal and rate of lymphatic elimination of 3 different wavelengths of Q-switched Nd-YAG laser (532nm, 1064nm, combination 532 + 1064). Methods: In this study we examined lymphatic elimination and the effect of 532 nm, 1064 nm, and the combination (532 + 1064 nm) wavelength of laser pulse for the possible lymphatic cleansing mechanism of black pigmented tattoos. This study was performed on 18 New-Zealand rabbits, black pigmented tattoos were engraved on the back and the four extremities of the animals. 532 nm wavelength of Q switched Nd: YAG laser beam was applied on the left upper and bilateral lower extremities of the rabbits. During this period, excisional skin biopsies and lymph node biopsies were performed on days 7, 14 and 21. Results: Day 21 lymph node biopsies revealed mixed type of reactive hyperplasia and intracellular pigments were markedly seen in the laser treatment group and no intracellular tattoo pigment was seen in the control group. Conclusion: The findingd of this study indicate that lymphatic elimination may be one of the significant mechanisms of tattoo removal and the application of different wavelengths of Q-switched Nd-YAG laser do not show statistically significant differences in tattoo removal.

Share and Cite:

S. Irkoren, C. Demirdover, B. Akad and M. Gorgu, "The Q-Switched Nd: YAG Laser in Tattoo Removal and the Effect of Lymphatic Elimination: An Experimental Study in Rabbits," Surgical Science, Vol. 2 No. 5, 2011, pp. 262-268. doi: 10.4236/ss.2011.25058.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] C. Jack, A. Adwani and H. Krishnan, “Tattoo Pigment in an Axillary Lymph Node Simulating Metastatic Malignant Melanoma,” International Seminars In Surgical Oncology, Vol. 1, No. 2, 2005, p. 28. doi:10.1186/1477-7800-2-28
[2] T. Friedman, M. Westreich, S. N. Mozes, A. Dorenbaum and O. Herman, “Tattoo Pigment in Lymph Nodes Mi-micking Metastatic Malignant Melanoma,” Plastic and Reconstructive Surgery, Vol. 111, No. 6, 2003, pp. 2120- 2122. doi:10.1097/01.PRS.0000057101.95872.A1
[3] B. D. Zelickson, D. A. Mehregan, A. A. Zarrin, C. Coles, P. Hartwig, S. Olson and J. Leaf-Davis, “Clinical, Histo-logic and Ultrastructural Evaluation of Tattoos Treated with Three Laser Systems,” Lasers in Surgery and Medi-cine, Vol. 15, No. 4, 1994, pp. 364-372. doi:10.1002/lsm.1900150406
[4] D. M. Ho, R. London, G. B. Zimmerman and D. A. Young, “Laser-Tattoo Removal—A Study of the Me-chanism and the Optimal Treatment Strategy via Computer Simulations,” Lasers in Surgery and Medicine, Vol. 30, No. 5, 2002, pp. 389-397. doi:10.1002/lsm.10065
[5] J. E. Ferguson, S. M. Andrew, C. J. P. Jones and P. J. August, “The Q Switched Neodymium: YAG Laser and Tattoos: A Microscopic Analysis of Laser-Tattoo Interac-tions,” British Journal of Dermatology, Vol. 137, No. 3, 1997, pp. 405-410. doi:10.1111/j.1365-2133.1997.tb03747.x
[6] M. L. Leuenberger, M. W. Mulas, T. R. Hata, M. P. Goldman, R. E. Fitzpatrick and J. M. Grevelink, “Com-parison of the Q-Switched Alexandrite, Nd: YAG, and Ruby Lasers in Treating Blue Black Tattoos,” Dermato-logic Surgery, Vol. 25, No. 1, 1999, pp. 10-14. doi:10.1046/j.1524-4725.1999.08122.x
[7] J. E. Ferguson and P. J. August, “Evaluation of the Nd: YAG Laser for Treatment of Amateur and Professional Tattoos,” British journal of dermatology, Vol. 135, No. 4, 1996, pp. 586-591. doi:10.1111/j.1365-2133.1996.tb03836.x
[8] S. L. Kilmer and R. R. Anderson, “Clinical use of the Q-Switched Ruby and the Q-Switched Nd: YAG( 1064 nm and 532 nm) Lasers for Treatment of Tattoos,” Journal of Dermatologic Surgery & Oncology, Vol. 19, No. 4, 1993, pp. 330-338.
[9] S. L. Kilmer, M. S. Lee, J. M. Grevelink, T. J. Flotte and R. R. Anderson, “The Q-Switched Nd: YAG Laser Effec-tively Treats Tattoos. A Controlled, Dose Response Stu- dy,” Archives of Dermatology, Vol. 129, No. 8, 1993, pp. 971-978. doi:10.1001/archderm.129.8.971
[10] S. E. Dozier, D. G. Diven, D. Jones, et al., “The Q-Swi- tched Alexandrite Laser’s Effects on Tattoos in Guinea Pigs and Harvested Human Skin,” Dermatologic Surgery, Vol. 21, No. 3, 1995, pp. 237-240.
[11] R. O. Gregory, “Overview of Laser in Plastic Surgery,” Clinics in Plastic Surgery, Vol. 25, No. 1, 1998, pp. 6-10.
[12] R. O. Gregory, “Laser Physics and Physiology,” Clinics in Plastic Surgery, Vol. 25, No. 1, 1998, pp. 89-93.
[13] E. V. Ross, S. Yashar, N. Michaud, R. Fitzpatrick, R. Geronemus, W. D. Tope and R. R. Anderson, “Tattoo Darkening and Nonresponse after Laser Treatment. A Possible Role for Titanium Dioxide,” Archives of Der-matology, Vol. 137, 2001, pp. 33-37.
[14] B. E. DiBernardo and A. Cacciarelli, “Cutaneous Lasers,” Clinics in Plastic Surgery, Vol. 32, No. 2, 2005, pp. 141- 150. doi:10.1016/j.cps.2004.11.008
[15] K. R. Suchin and S. S. Greenbaum, “Successful Treatment of a Cosmetic Tattoo Using a Combination of Lasers,” Dermatologic Surgery, Vol. 30, No. 1, 2004, pp. 105-107. doi:10.1111/j.1524-4725.2004.30024.x
[16] G. Jimenez, E. Weiss and J. M. Spencer, “Multiple Color Changes Following Laser Therapy of Cosmetic Tattoos,” Dermatologic Surgery, Vol. 28, No. 2, 2002, pp. 177-179. doi:10.1046/j.1524-4725.2002.00161.x
[17] A. Jones, P. Roddey, I. Orengo and T. Rosen, “The Q-Switched ND: YAG Laser Effectively Treats Tattoos in Darkly Pigmented Skin,” Dermatologic Surgery, Vol. 22, 1996, pp. 990-1001.
[18] S. L. Kilmer, “Laser Treatment of Tattoos,” Lasers in Dermatology, Vol. 15, No. 3, 1997, pp. 409-417.
[19] R. R. Anderson, “Regarding Tattoos,” Archives of Der-matology, Vol. 137, 2001, pp. 210-212.
[20] C. Gundogan, B. Greve, I. Hausser and C. Raulin, “Re-pigmentierung Persistierender Laserinduzierter Hypo-pigmentierungen Nach Tatowierungs-Entfernung Mit dem Excimerlaser,” Hautarzt, Vol. 55, No. 6, 2004, pp. 549- 552. doi:10.1007/s00105-004-0718-3
[21] S. L. Kilmer, “Laser Eradication of Pigmented Lesions and Tattoos,” Dermatologic Clinics, Vol. 20, No. 1, 2002, pp. 37-53. doi:10.1016/S0733-8635(03)00057-3
[22] H. J. Zikrin, I. Avinoach and P. Edelwitz, “A Tattoo and Localized Lymphadenopathy: A Case Report,” Cutis, Vol. 67, 2001, pp. 471-472.
[23] T. Alster, “Q-Switched Alexandrite (755nm) Laser Treat- ment of Professional and Amateur Tatoos,” Journal of the American Academy of Dermatology, Vol. 33, No. 1, 1995, pp. 69-73. doi:10.1016/0190-9622(95)90013-6

Copyright © 2024 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.