Post Liver Transplantation Lympho Proliferative Disorder, Classical Hodgkins Lymphoma Type—A Case Report

Indu R. Nair^1*, Annie Jojo¹, Sudhindran Surendran², Dinesh Balakrishnan²

¹Department of Pathology, Amrita Institute of Medical Sciences, Amrita Viswavidyapeetam, Kochi, India.
²Department of Surgical Gastroenterology, Amrita Institute of Medical Sciences, Amrita Viswavidyapeetam, Kochi, India.

DOI: 10.4236/ijcm.2014.518146                

Abstract

Post transplantation lymphoproliferative disorder is a lymphoid/plasmacytic proliferation that develops as a consequence of immunosuppression in a recipient of a solid organ/bone marrow/stem cell allograft. The incidence reported in literature in post liver transplant patients is 1% - 2%. This case was of a 16-year-old boy who underwent liver transplantation for fulminant hepatic failure and subsequently developed PTLD. Morphologically and immunohistochemically, it was Hodgkin’s lymphoma like PTLD, which was the least common type reported in literature.

Keywords

Liver Transplant, Post Transplant Lymphoproliferative Disorder, Classical Hodgkin’s Lymphoma Like

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1]	International Agency for Research on Cancer (IARC) (2008) WHO Classification of Tumours of Hematopoietic and Lymphoid Tissues. 4th Edition.
[2]	Jain, A., Nalesnik, M., et al. (2002) Posttransplant Lymphoproliferative Disorders in Liver Transplantation. A 20-Year Experience. Jorge Reyes Annals of Surgery, 236, 429-437.
[3]	Parker, A., Bowles, K., Bradley, J.A., et al. (2010) Diagnosis of Post-Transplant Lymphoproliferative Disorder in Solid Organ Transplant Recipients—BCSH and BTS Guidelines. British Journal of Haematology, 149, 675-692.