On a cardiac work rate based on ventricular pressure measurement


We presented a cardiac work rate for one cycle cardiac based on the area of a Pressure Phase Plane, the velocity of activation and relaxation of the pressure curve, the interval of time and the variation of the pressure measurement on that cycle. We established an algebraic model to the Pressure Phase Plane area with a complete correlation of that model and the laboratory data for normal hypertensive and hypertrophied rat hearts (r = 0.99). We have obtained disjoint intervals for the cardiac work rate of the control group and the hypertrophied rat hearts as a consequence of the application of our algebraic model in those data acquisition.

Share and Cite:

Camilo, L. , Vassallo, D. and Aquino, R. (2013) On a cardiac work rate based on ventricular pressure measurement. Journal of Biomedical Science and Engineering, 6, 934-942. doi: 10.4236/jbise.2013.69114.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] Eucker, S.A., Lisaukskas, J.B., Singh, J. and Kovàcs, S.J. (2001) Phase plane analysis of left ventricular hemodynamics. Journal of Applied Physiology, 90, 2238-2244.
[2] Vassalo, D.V. and Paes de Carvalho, A. (1979) Phase plane determination of the mechanical properties of the miocardium. Acta Physiol Pharmacol Latinoam, 29, 137-149.
[3] Chung, C.S., Strunc, A., Oliver, R. and Kovács, S.J. (2006) Diastolic ventricular-vascular stiffness and relaxation relation: Elucidation of coupling via Pressure Phase Plane-derived indexes. American Journal of Physiology-heart and Circulatory Physiology, 291, H2415-2423. http://dx.doi.org/10.1152/ajpheart.00257.2006
[4] Castellano, E.E. (1978) Analytical description of forcetime and force-velocity relations of isometric contractions in feline isolated heart muscle and in the intact heart. Circulation Research, 42, 686-693. http://dx.doi.org/10.1161/01.RES.42.5.686
[5] Fung, Y.-C. (1970) Mathematical representation of the mechanical properties of the heart muscle. Journal of Biomechanics, 3, 381-404. http://dx.doi.org/10.1016/0021-9290(70)90012-6

Copyright © 2024 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.