CT Guided Bone Marrow Aspiration and Core Biopsy


Hemorrhagic complications related to bone marrow aspiration and trephine biopsy are uncommon. Risk factors include thrombocytopenia, myeloproliferative disorders, concurrent use of anticoagulants, and obesity. Here we describe our technique for bone marrow aspiration and biopsy of the posterior iliac crest using CT guidance. Our technique ensures needle passage only through subcutaneous fat and bone, avoiding muscle and neurovascular structures, as well as controlled and precise needle advancement within bone. This technique should be considered for use in patients that are at increased risk for procedure related complications, particularly obese patients, where surface anatomical landmarks may prove unreliable.

Share and Cite:

C. Badiola, F. Scappaticci and D. Brahaj, "CT Guided Bone Marrow Aspiration and Core Biopsy," Open Journal of Radiology, Vol. 2 No. 2, 2012, pp. 55-56. doi: 10.4236/ojrad.2012.22010.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] B. J. Bain, “Bone Marrow Biopsy Morbidity and Mortality,” British Journal of Haematology, Vol. 121, No. 6, 2003, pp. 949-951. doi:10.1046/j.1365-2141.2003.04329.x
[2] S. Malempati, S. Joshi, S. Lai, et al., “Bone Marrow Aspiration and Biopsy,” New England Journal of Medicine, Vol. 361, 2009, p. e28.
[3] R. M. Lowenthal, B. V. Taylor, R. Jones andA. Beasly, “Severe Persistent Sciatic Pain and Weakness Due to a Gluteal Artery Pseudoaneurysm as a Complication of Bone Marrow Biopsy,” Journal of Clinical Neuroscience, Vol. 13, No. 3, 2006, pp. 384-385. doi:10.1016/j.jocn.2005.03.027
[4] P. Salem, M. K. Wolverson, H. J. Reimers and G. C. Kudva, “Complications of Bone Marrow Biopsy,” British Journal of Haematology, Vol. 121, No. 6, 2003, p. 821. doi:10.1046/j.1365-2141.2003.04328.x
[5] M. Luoni, et al., “Retroperitoneal Hemorrhage Following Bone Marrow Biopsy,” Haematologica, Vol. 79, No. 1, 1994, pp. 70-72.
[6] J. M. Mathis and W. Wong, “Percutaneous Vertebroplasty, Technical Considerations,” Journal of Vascular and Interventional Radiology, Vol. 14, No. 8, 2003, pp. 953-960. doi:10.1097/01.RVI.0000083255.29749.A8

Copyright © 2024 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.