Influence of Thioctic Acid on the Hyperinsulinemia and Ovarian Volume in Female Patients with Polycystic Ovary Syndrome

L. A. Ivanova

Endocrinology Department, Kuban State Medical University, Krasnodar, Russia.

DOI: 10.4236/ojemd.2015.54005                

Abstract

45 female patients with polycystic ovary syndrome took thioctic acid (Thioctacid-HR), 600 mg (n = 25) or high protein diet (n = 20). Fast insulin and glucose stimulus insulin were investigated before and after 3 months taken treatment. The use of thioctic acid, 600 mg is a new effective pathogenetics therapy of polycystic ovary syndrome on influence of hyperinsulinemia, HOMA-IR index and ovary volume in female patients with polycystic ovary syndrome.

Keywords

Thioctic Acid, Hyperinsulinemia, Polycystic Ovary Syndrome

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1]	Ivanova, L.A. (2004) Comparison of Treatment of Adiposity by Different Methods. International Journal of Obesity and Related Metabolic Discorders: 13th European Congress on Obesity, 28, 132.
[2]	Holte, J. (1998) Polycystic Ovary Syndrome and Insulin Resistance: Thrifty Genes Struggling with Overfeeding and Sedentary Life Style. Journal of Endocrinological Investigation, 21, 589-601.
[3]	Ivanova, L.A. (2007) Thioctic Acid and Hormonal Replacement Treatment in Men and Women with 2 Type Diabetes and Obesity. Journal of Clinical Lipidology, 1, 499.
[4]	Ivanova, L.A. (2011) Influence of Thioctic Acid on Metabolic Syndrome. 4th International Congress on Prediabetes and the Metabolic Syndrome, Madrid, 6-9 April 2011, 92.
[5]	Ivanova, L.A. (2009) Influence of Thioctic Acid on the Metabolic Parameters during Long Treatment of Diabetic Peripheral Neuropathy in Type 2 Diabetics. ISDN/Neurodiab Conference, Canada, 20-21.
[6]	Palomba S. et al. (2008) Role of Metformin in Patients with Polycystic Ovary Syndrome: The State of the Art. Minerva Ginecologica, 60, 77-82.