Radiated Ultrashort High-Power Electromagnetic Pulses Induce ATP Release in B16F10 Murine Melanoma Cells

DOI: 10.4236/jemaa.2015.73008   PDF   HTML   XML   3,590 Downloads   4,416 Views   Citations


Ultrawideband electromagnetic pulses with high amplitude and short duration are reported to affect several aspects of cell physiology. They are usually delivered to the living material through electrodes in small dedicated chambers. Here we showed, using a totally different experimental setup, that radiated EM pulses illuminating the living material through a specialized antenna (without any direct contact) are able to trigger a rapid release of ATP in cultured murine cells that was concomitant with a drop of intracellular AEC. Despite this rapid and strong response, we found that cell viability and clonogenicity were only slightly affected by the EMF exposure.

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Macaire, S. , Catrain, A. , Tortel, S. , Joly, J. , Girard, S. , Bonnet, P. and Vian, A. (2015) Radiated Ultrashort High-Power Electromagnetic Pulses Induce ATP Release in B16F10 Murine Melanoma Cells. Journal of Electromagnetic Analysis and Applications, 7, 66-74. doi: 10.4236/jemaa.2015.73008.

Conflicts of Interest

The authors declare no conflicts of interest.


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