Risk Factors of First Acute Myocardial Infarction: Comparison of Elderly and Non-Elderly: A 24-Year Study

Soheila Dabiran; Behrooz Khaleghi Manesh; Farahnaz Khajehnasiri

doi:10.4236/aar.2015.41002

Home > Journals > Biomedical & Life Sciences | Medicine & Healthcare > AAR

AAR> Vol.4 No.1, January 2015

Share This Article:

Risk Factors of First Acute Myocardial Infarction: Comparison of Elderly and Non-Elderly: A 24-Year Study ()

Abstract Full-Text HTML XML

Download as PDF (Size:2670KB) PP. 13-17

DOI: 10.4236/aar.2015.41002 2,602 Downloads 3,644 Views Citations

Author(s) Leave a comment

Soheila Dabiran^1*, Behrooz Khaleghi Manesh², Farahnaz Khajehnasiri¹

Affiliation(s)

¹Department of Community Medicine, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
²Department of Internal Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

ABSTRACT

Although risk factors of Ischemic Heart Disease (IHD) are well known, knowledge about the distribution of these risk factors in different subgroups of patients can be used for designing preventive programs. The aim of this study was to assess differences of prevalence of IHD risk factors in elderly and non-elderly patients in their first Acute Myocardial Infarction (AMI). In this retros-pective study, elderly (age > 65; n = 1060) and non-elderly (age ≤ 65; n = 2228) patients with first AMI who were admitted into four teaching hospitals in Tehran between 1982 and 2005 were recruited. Risk factors containing male gender, systolic and diastolic hypertension (HTN), diabetes, hypertriglyceridemia, hypercholesterolemia, smoking and family history of IHD were compared between the two groups. Among different risk factors, diabetes and systolic HTN were more common in elderly than their non-elderly counterparts, and male gender, smoking, family history of IHD and dyslipidemia were more common in non-elderly patients than elderly ones (p < 0.05 for all comparison). Diastolic HTN showed no significant difference between the two groups. Findings of this study, stating difference of prevalence of risk factors in two elderly and non-elderly groups, can be used by health policy makers to conduct preventive programs for AMI in this country.

KEYWORDS

Acute Myocardial Infarction, Risk Factors, Elderly

Cite this paper

Dabiran, S. , Manesh, B. and Khajehnasiri, F. (2015) Risk Factors of First Acute Myocardial Infarction: Comparison of Elderly and Non-Elderly: A 24-Year Study. Advances in Aging Research, 4, 13-17. doi: 10.4236/aar.2015.41002.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1]	Gaziano, T.A. and Micheal Gasiano, J. (2011) Global Burden of Cadiovascular Disease. In: Bonow, R.O., Mann, D.L., Zipes, D.P. and Libby, P., Eds., Braunwald’s Heart Disease: A Textbook of Cardiovascular Medicine, 9th edition, W.B. Saunders Company, Philadelphia, 1-20.

[2]	Schwartz, J.B. and Zipes, D.P. (2011) Cardiovascular Disease in the El-derly. In: Bonow, R.O., Mann, D.L., Zipes, D.P. and Libby, P., Eds., Braunwald’s Heart Disease: A Textbook of Cardiovascular Medicine, 9th edition, W.B. Saunders Company, Philadelphia, 1727-1756.

[3]	Newby, L.K. and Douglas, P.S. (2012) Cardiovascular Disease in Women. In: Bonow, R.O., Mann, D.L., Zipes, D.P. and Libby, P., Eds., Braunwald’s Heart Disease: A Textbook of Cardiovascular Medicine, 9th edition, W.B. Saunders Company, Philadelphia, 1757-1769.

[4]	Mamun, A.A., Peeters, A., Barendregt, J., Willekens, F., Nusselder, W. and Bonneux, L. (2004) Smoking Decreases the Duration of Life Lived with and without Cardiovascular Disease: A Life Course Analysis of the Framingham Heart Study. European Heart Journal, 25, 409-415.

[5]	Kitamura, A., Iso, H., Iida, M., Naito, Y., Sato, S., Jacohs Jr., D.R., Nakamura, M., Shimamoto, T. and Shimamoto, T. (1994) Factor among Japanese Men from 1960 to 1994. The American Journal of Medicine, 112, 104-109.http://dx.doi.org/10.1016/S0002-9343(01)01053-1

[6]	Roger, V.L., Jacobsen, S.J., Weston, S.A., Goraya, T.Y., Killian, J. and Reeder, G.S. (2002) Trends in the Incidence and Survival of Patients with Hospitalized Myocardial Infarction, Olmsted country, Minnesota, 1979 to 1994. Annals of Internal Medicine, 136, 341-348.

[7]	Brown, N., young, T., Gray, D., Skene, A.M. and Hampton, J. (1997) Inpatient Death in Patient Death from Acute Myocardial Infarction, 1982-1992: Analysis of Date in the Nottingham Heart Attack Registers. British Medical Journal, 315, 159-169. http://dx.doi.org/10.1136/bmj.315.7101.159

[8]	Chiara, D.I., Chiarella, A., Saronittos, F., Lucci, D., Bolognese, L., De Servi, S., Greco, C., Boccanelli, A., ZonZon, P., Coccolinl, S. and Maggioni, A.P. ( 2003) Epidemiology of Acute Myocardial Infarction in the Italian CCU Network: the BLITZ Study. European Heart Journal, 24, 1611-1612.

[9]	Cong, N.D. and Dung, H.T. (2014) The Risk Factors of Acute Coronary Syndrome in Patients over 65 Years Old at Thong Nhat Hospital of Ho Chi Minh City, Vietnam. Journal of Atherosclerosis and Thrombosis, 21, S36-S41.http://dx.doi.org/10.5551/jat.21_Sup.1-S36

[10]	Bottlieb, S., Boyko, V., Harpaz, D., Hod, H. and Cohen, M. (1999) Long-Term (Three-Year) Prognosis of Patients Striated with Reperfusion Conservatively after a Cut Myocardial Infarction. Journal of American College of Cardiology, 34, 70-82. http://dx.doi.org/10.1016/S0735-1097(99)00152-7

[11]	Psaty, B.M., Furberg, C.D., Kuller, L.H., Cushman, M., Savage, P.J., Levine, D., O’Leary, D.H., Bryan, R.N., Anderson, M. and Lumley, T. (2001) Association between Blood Pressure Level and the Risk of Myocardial Infarction, Stroke, and Total Mortality. JAMA Internal Medicine, 161, 1183-1192. http://dx.doi.org/10.1001/archinte.161.9.1183

[12]	Gaziano, J.M., Hennekens, C.H., O’Donnell, C.J., Breslow, J.L. and Buring, J.E. (1997) Fasting Triglycerides, High-Density Lipoprotein, and Risk of Myocardial Infarction. Circulation, 96, 2520-2525. http://dx.doi.org/10.1161/01.CIR.96.8.2520

[13]	Khan, M.M.H., Khan, A., Kraemer, A. and Mori, M. (2009) Prevalence and Correlates of Smoking among Urban Adult Men in Bangladesh: Slum versus Non-Slum Comparison. BMC Public Health, 9, 149. http://dx.doi.org/10.1186/1471-2458-9-149

[14]	Rastogi, T., Jha, P., Reddy, K.S., Prabhakaran, D., Spiegelman, D., Stampfer, M.J., Willett, W.C. and Ascherio, A. (2005) Bidi and Cigarette Smoking and Risk of Acute Myocardial Infarction among Males in Urban India. Tobacco Control, 14, 356-358. http://dx.doi.org/10.1136/tc.2005.011965

[15]	Shiraishi, J., Kohno, Y., Yamagushi, S., Arihara, M., Hadase, M., Hyogo, M., Yagi, T., Shima, T., Sawada, T., Tatsumi, T., Azuma, A. and Matsubara, H. (2006) Medium-Term Prognosis of Young Japanese Adults Having Acute Myocardial Infarction. Circulation Journal, 70, 518-524. http://dx.doi.org/10.1253/circj.70.518

[16]	Shiraishi, J., Kohno, Y., Yamagushi, S., Arihara, M., Hadase, M., Hyogo, M., Yagi, T., Shima, T., Sawada, T., Tatsumi, T., Azuma, A. and Matsubara, H. (2005) Acute Myocardial Infarction in Young Japanese Adults. Clinical Manifestations and In-Hospital Outcome. Circulation Journal, 69, 1454-1458. http://dx.doi.org/10.1253/circj.69.1454

[17]	Parish, S., Collins, R., Peto, R., Youngman, L., Barton, J., Jayne, K., et al. (1995) Cigarette Smoking, Tar Yields, and Non-Fatal Myocardial Infarction: 14000 Cases and 32000 Controls in the United Kingdom. British Medical Journal, 311, 471-477.

[18]	Critchley, J.A. and Capewell, S. (2003) Mortality Risk Reduction Associated with Smoking Cessation in Patients with Coronary Heart Disease: A Systematic Review. Journal of the American Medical Association, 290, 86-97.

[19]	Mahonen, M.S., McElduff, P., Dobson, A.J., Kuulasmaa, K.A. and Evans, A.E. (2004) Current Smoking and the Risk of Non-Fatal Myocardial Infarction in the WHO MONICA Project Populations. Tobacco Control, 13, 244-250. http://dx.doi.org/10.1136/tc.2003.003269

[20]	Ottesen, M.M., Jorgensen, S., Kjoller, E., Videbak, J., Kober, L. and Torp-Pedersen, C. (1999) Age-Distribution, Risk Factors and Mortality in Smokers and Non-Smokers with Acute Myocardial Infarction: A Review. European Journal of Preventive Cardiology, 6, 307-309.

[21]	Negri, E., La Vecchia, C., Nobili, A., D’Avanzo, B. and Bech, S. (1994) Cigarette Smoking and Acute Myocardial Infarction. A Case-Control Study. European Journal of Epidemiology, 10, 361-366.

[22]	Srnivasan, S.R. and Berenson, G.S. (2005) Cardiovascular Risk Factors in Youth with Implications for Aging: The Bogalusa Heart Study. Neurobiology of Aging, 26, 303-307. http://dx.doi.org/10.1016/j.neurobiolaging.2004.05.009

[23]	Arnold, S.V., Lipska, K.J., Li, Y., McGuire, D.K., Goyal, A., Spertus, J.A. and Kosiborod, M. (2014) Prevalence of Glucose Abnormalities among Patients Presenting with an Acute Myocardial Infarction. American Heart Journal, 168, 466-470.