Characterization of Tuberculosis Cases Presenting in a Tertiary Healthcare Facility in South-Eastern Nigeria


Background: Tuberculosis is second only to HIV/AIDS as the greatest killer worldwide, due to a single infectious agent. Directly Observed Treatment Short-Course (DOTS) is presently the WHO recommended programme to fight tuberculosis worldwide. There is need to understand the characteristics of patients who receive treatment for tuberculosis. This will help modify the strategies to fight the scourge of tuberculosis. Methods: This was a retrospective study conducted at the DOTS clinic at Nnamdi Azikiwe University Teaching Hospital Nnewi, Anambra State, Nigeria. The records of patients who received treatment from the clinic from 1st January 2012 to 31st December 2012 were reviewed. Three hundred and fifteen patients were included in the study. Important characteristics of the patients were retrieved. Associations between patients’ characteristics were determined using relevant tests of significance. Results: Three hundred and fifteen patients were included in the study. There were more male patients (59%). The reproductive age group (37.5%) was more than the other age groups. Mean age was 33.1 (±18.5) years. There were more rural patients (50.2%) than urban patients (49.8%). There were more pulmonary TB patients (87.3%) than extrapulmonary TB patients (12.7%). There were more sputum AFB negative patients (45.4%) than positive patients (41.3%). There were more HIV negative patients (59.4%) than positive patients (40.6%). Conclusion: This study demonstrated some important characteristics of tuberculosis patients. Such knowledge if taken into consideration in the tuberculosis control programme will definitely improve the outcome of the programme.

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Adinma, E. , Azuike, E. , Nwabueze, S. , Nnebue, C. , Azuike, E. , Obi, D. , Iloghalu, I. , Okonkwo, K. and Ohamaeme, M. (2014) Characterization of Tuberculosis Cases Presenting in a Tertiary Healthcare Facility in South-Eastern Nigeria. Open Journal of Preventive Medicine, 4, 723-729. doi: 10.4236/ojpm.2014.49082.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] Haslett, C., Chilvers, E.R., Hunter, J.A. and Boon, N.A. (1999) Davidson’s Principles and Practice of Medicine. 18th Edition, Churchill Livingston, New York.
[2] Lucas, A.O. and Gilles, H.M. (2003) Short Textbook of Public Health Medicine for the Tropics. 4th Edition. Arnord Publishers, London, 159.
[3] World Health Organisation (2014) Tuberculosis Fact Sheet.
[4] United States Agency for International Development (USAID) (2014) TB Care Project, Country Details, Nigeria.
[5] Park, K. (2005) Preventive and Social Medicine. 18th Edition. M/S Banarsidas Bhanot, Jabalpur, 890.
[6] Ogboi, S.J., Idris, S.H., Olayinka, A.T. and Ilyas, J. (2010) Socio-Demographic Characteristics of Patients Presenting with Pulmonary Tuberculosis in A Primary Health Centre, Zaria, Nigeria. Journal of Medical Laboratory and Diagnosis, 1, 11-14.
[7] Ekwueme, O.C., Ezeoke, U.E. and Mgbeokwere, U. (2009) The Prevalence and Socio-Demographic Characteristics of Persons with TB and TB/HIV Co-Infection at the Chest Clinic of the University of Nigeria Teaching Hospital, Enugu, Nigeria. Journal of College of Medicine, 14, 6-17.
[8] Hamid, S., Syed, A.H. and Ali, I. (2012) Sociodemographic Factors Associated with Sputum Positivity Rates for Tuberculosis in Patients with Cough in Srinagar Hospital, India. Pacific Journal of Medical Sciences, 9, 47-52.
[9] Donald, C., Uday, S.S., Sidhyartha, M. and Deepak, S. (2010) Socio-Demographic Profiles of the Delayed Diagnosed Patients in RNTCP, Anand District. Healthline, 1, 45-48.
[10] Lawn, S.D., Bekker, L, Middelkoop, K., Myer L. and Wood R. (2006) Impact of HIVI Infection on the Epidemiology of Tuberculosis in a Peri-Urban Community in South Africa: The Need for Age-Specific Interventions. Clinical Infectious diseases, 42, 1040-1047.
[11] Muhammad, U.M., Ubeera, S., Hussain, M.A., Anum, S., Fatima, O., et al. (2011) Urban-Rural Inequities in Knowledge, Attitudes and Practices Regarding Tuberculosis in Two Districts of Pakistan’s Punjab Province. International Journal for Equity in Health, 10, 8.
[12] Rajewswani, R., Balasubramanian, R., Muniyadi, M., Geetharamani, S., Theresa, X. and Venkatessa, P. (1999) Socio-Economic Impact of Tuberculosis on Patients and Family in India. The International Journal of Tuberculosis and Lung Disease, 3, 869-877.
[13] Sreeramareddy, C.T., Panduru, K.V., Verma, S.C., Joshi, H.S. and Bates, M.N. (2008) Comparison of Pulmonary and Extrapulmonary Tuberculosis in Nepal-A Hospital-Based Retrospective Study. BMC Infectious Diseases, 8, 8.
[14] Noertjojo, K., Tam, C.M., Chan, S.L. and Chan-Yeung, M.M. (2002) Extra-Pulmonary and Pulmonary Tuberculosis in Hong Kong. The International Journal of Tuberculosis and Lung Disease, 6, 879-886.
[15] Musellin, B., Erturan, S., Sonmez, D.E. and Ongen, G. (2005) Comparison of Extrapulmonary and Pulmonary Tuberculosis Cases: Factors Influencing the Site of Reactivation. International Journal of Tuberculosis and Lung Disease, 9, 1220-1223.
[16] Sharma, S.K. and Mohan, A. (2012) Extrapulmonary Tuberculosis. Indian Journal of Medical Research, 136, 1129-1166.
[17] Datiko, D.G., Yassin, M.A., Chekol, L.T., Kabeto, L.E. and Lindtjorn, B. (2008) The Rate of TB/HIV Co-Infection Depends on the Prevalence of HIV Infection in a Community. BMC Public Health, 8, 266.
[18] John, M., Menezes, N. and Grobusch, M.P. (2007) High Tuberculosis and HIV Co-infection Rate, Johannesburg. Emerging Infectious Diseases, 13, 795-796.
[19] Dharma, S.K., Aggarwal, P.S. and Saha, P.K. (2003) Increasing HIV Seropositivity among Adult Tuberculosis Patients in Delhi. Indian Journal of Medical Research, 117, 239-242.
[20] Centres for Disease Control and Prevention (2014) HIV/AIDS Statistics.
[21] World Health Organisation (WHO) HIV/AIDS Fact Sheet.
[22] Marlink, R.G. and Kotin, A.G. (2004) Global AIDS Crisis: A Reference Handbook. ABC-CLIO Inc., Carlifonia, 54.
[23] Federal Ministry of Health of Nigeria (2012) 2010 National HIV Sero-Prevalence Sentinel Survey. Federal Ministry of Health, Abuja.
[24] Obidoa, C.A. and Cromley, R.G. (2012) A Geographical Analysis of HIV/AIDS Infection in Nigeria, 1991-2001. Journal of Social, Behavioural and Health Sciences, 6, 13-29.

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