Acute Respiratory Distress Syndrome (ARDS) Case Report after a Caesarean Section Related to the Immune Reconstitution Inflammatory Syndrome


During pregnancy, a cellular immunosuppressant status is produced. It is characterized by anti-inflammatory cellular responses that allow embryonic implantation. The reversal of these changes during the postpartum period may result in overt clinical manifestations of otherwise quiescent or latent infections. We present an Acute Respiratory Distress Syndrome (ARDS) case after a caesarean section related to the Immune Reconstitution Inflammatory Syndrome (IRIS) in a Guinean black woman. The patient was treated with large doses of corticosteroids showing a great clinical and radiological improvement.

Share and Cite:

Ruiz, Á. , Cortés, P. , Sánchez, I. , Losa, J. , Murillo, M. and del Valle y Manzano, S. (2014) Acute Respiratory Distress Syndrome (ARDS) Case Report after a Caesarean Section Related to the Immune Reconstitution Inflammatory Syndrome. Open Journal of Anesthesiology, 4, 197-201. doi: 10.4236/ojanes.2014.48028.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] Singh, N. and Perfect, J.R. (2007) Immune Reconstitution Syndrome and Exacerbation of Infections after Pregnancy. Clinical Infectious Diseases, 45, 1192-1199.
[2] Meintjes, G., et al. (2008) International Network for the Study of HIV-Associated IRIS. Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome: Case Definitions for Use in Resource-Limited Settings. The Lancet Infectious Diseases, 8, 516-523.
[3] Meintjes, G., et al. (2010) Randomized Placebo-Controlled Trial of Prednisone for paradoxical Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome. AIDS, 24, 2381-2390.
[4] Agarwal, R. and Gupta, D. (2009) Tuberculous Sarcoidosis: Is It a Separate Entity? Lung India, 26, 61-62.
[5] Baudin, B. (2005) [Angiotensin I-Converting Enzyme (ACE) for Sarcoidosis Diagnosis]. Pathologie Biologie (Paris), 53, 183-188.
[6] Lynch III, J.P., Kazerooni, E.A. and Gay S.E. (1997) Pulmonary Sarcoidosis. Clinics in Chest Medicine, 18, 755-785.
[7] Ellafi, M. and Valeyre, D. (1999) Sarcoidosis and Pregnancy. Revue de Pneumologie Clinique, 55, 335-337.
[8] Amarapurkar, A1. and Agrawal, V. (2006) Liver Involvement in Tuberculosis—An Autopsy Study. Trop Gastroenterol, 27, 69-74.
[9] Paramothayan, N.S., Lasserson, T.J. and Jones, P.W. (2005) Corticosteroids for Pulmonary Sarcoidosis. Cochrane Database of Systematic Reviews, 18, Article ID: CD001114.
[10] Narita, M., Yamada, S., Kikuta, H. and Togashi, T. (2000) Reconstitution of Humoral Immunity During Pregnancy. American Journal of Reproductive Immunology, 44, 148-152.

Copyright © 2023 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.