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Solitary Plasmacytoma of the Zygoma in a 70-Year-Old Nigerian: A Case Report and Review of Literature

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DOI: 10.4236/ijohns.2014.34036    1,937 Downloads   2,522 Views  

ABSTRACT

Purpose: Solitary bone plasmacytoma [SBP] is a localised variant of plasma cell tumor which commonly affects the axial skeleton but rarely found in the maxillofacial region. We hereby report an unusual case of solitary plasmacytoma of the right zygomatic bone in a 70-year-old Nigerian. Case Report: The patient presented with a painless right zygomatic swelling of 2 years duration. Examination showed that the swelling was of mixed consistency [mostly bony but firm in some areas] and it measured about 8 × 8 cm. Radiographic examination revealed an osteolytic lesion over the right zygoma with involvement of the apex and lateral wall of the antrum. An initial working diagnosis of ossifying fibroma was made and the patient was scheduled for surgery. Histological staining with H & E and immunohistochemistry of the surgical specimen however confirmed a diagnosis of SBP. Serum monoclonal protein and Bence Jones proteinuria was negative throughout the follow up period. Conclusion: SBP of the maxillofacial region is amenable to surgery combined with postoperative radiotherapy. However, prognosis can be worsened with tumor recurrence or dissemination into MM. Thus patients with SBP must be closely followed up after treatment so that immediate therapeutic steps can be taken if recurrence or systemic dissemination is encountered.

Conflicts of Interest

The authors declare no conflicts of interest.

Cite this paper

Obimakinde, O. , Taiwo, O. , Lawal, A. , Adisa, A. , Okoje, V. and Arotiba, J. (2014) Solitary Plasmacytoma of the Zygoma in a 70-Year-Old Nigerian: A Case Report and Review of Literature. International Journal of Otolaryngology and Head & Neck Surgery, 3, 195-199. doi: 10.4236/ijohns.2014.34036.

References

[1] Rao, K., Priya, N.S., Umadevi, H.S., Smitha, T., Reshma, V. and Grace, S.A. (2011) Bone Plasmacytoma of the Maxilla: A Rare Case Report. International Journal of Clinical Dentistry, 2, 37-40.
[2] Gupta, A. and Bansal, P. (2011) Mandibular Swellimg—Can It Be Multiple Myeloma? Indian Journal of Dental Sciences, 3, 25-27.
[3] Dimopolous, M.A., Goldstein, J., Fuller, L., Delasalle, K. and Alexanian, R. (1992) Curability of Solitary Plasmacytoma of Bone. Journal of Clinical Oncology, 10, 587-590.
[4] Serena, M. and Pierpaolo, D.M. (2010) Solitary Plasmacytoma of the Jaw. Journal of Blood Medicine, 1, 33-38.
[5] Epstein, J.B., Voss, N.J. and Stenenson-Moore, P. (1984) Maxillofacial Manifestations of Multiple Myeloma. An Unusual Case and Review of Literature. Oral Surgery Oral Medicine Oral Pathology, 57, 267-271.
[6] Das, S.K., Saha, S., Bhowmic, A.K., Mukhejee, S. and Banerjee, S. (2004) Maxillary Swelling—A Rare Presentation of Solitary Plasmacytoma. Indian Journal of Otolaryngology and Head & Neck Surgery, 56, 213-215.
[7] Agostini, T., Sacco, R., Bertolai, R., Acocella, A. and Lazzeri, D. (2011) Solitary Plasmacytoma of the Jaw. Journal of Craniofacial Surgery, 22, 2-10.
http://dx.doi.org/10.1097/SCS.0b013e31822ec79a
[8] Rodriguez-Caballero, B., Sanchez-Santolino, S., Garcia-Montesinos-Perea, B., Garcia-Reija, M.F., Gomez-Roman, J. and Saiz-Bustillo, R. (2011) Mandibular Solitary Plasmocytoma of the Jaw: A Case Report. Medicina Oral Patologia Oral y Cirugia Bucal, 16, 647-650.
http://dx.doi.org/10.4317/medoral.16952
[9] Dimopolous, M.A., Moulopoulos, L.A., Maniatis, A. and Alexanian, R. (2000) Solitary Plasmacytoma of Bone and Asymptomatic Multiple Myeloma. Blood, 96, 2037-2044.
[10] Chang, M.Y., Shih, L.Y., Dunn, P., Leung, W.M. and Chen, W.J. (1994) Solitary Plasmacytoma of Bone. Journal of the Formosan Medical Association, 93, 307-402.
[11] Anil, S. (2007) Solitary Plasmacytoma of the Maxilla—A Case Report and Review of the Literature. General Dentistry Journal, 55, 39-43.
[12] Miller, F.R., Lavertu, P., Wanamaker, J.R., Bonafede, J. and Wood, B.G. (1998) Plasmacytomas of the Head and Neck. Otolaryngology—Head and Neck Surgery, 119, 614-618.
http://dx.doi.org/10.1016/S0194-5998(98)70021-X
[13] Mustoe, T.A., Fried, M.P., Goodman, M.L., Kelly, J.H. and Strome, M. (1984) Osteosclerotic Plasmacytoma of the Maxillary Bone [Orbital Floor]. Journal of Laryngology and Otology, 98, 929-938.
http://dx.doi.org/10.1017/S0022215100147735
[14] Canger, E.M. and Celenk, P. (2007) Mandibular Involvement of Solitary Plasmacytoma: A Case Report. Medicina Oral Patologia Oral y Cirugia Bucal, 12, 7-9.

  
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