Giant Vascular Eccrine Spiradenoma with Unusual Clinical Presentation: A Case Report


Giant Vascular Eccrine Spiradenoma (GVES) is a rare variant of Eccrine Spiradenoma (ES), a tumor that develops from the sweat gland. It differs from Eccrine Spiradenoma in its larger size and vascularity as well as propensity for bleeding and ulceration, which may cause a clinical misdiagnosis of vascular lesion or malignant tumor. All previously reported cases in English literature have been in older adults and the elderly, age range being from 49 to 84 years. Here a rare case of GVES in a young male presenting as a cutaneous chest wall lesion with bleeding, which was initially diagnosed as a vascular lesion clinically as well as on histopathology is reported.

Share and Cite:

Krishnan, K. and Thomas, A. (2014) Giant Vascular Eccrine Spiradenoma with Unusual Clinical Presentation: A Case Report. Open Journal of Pathology, 4, 21-24. doi: 10.4236/ojpathology.2014.42004.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] Al-Nafussi, A., Blessing, K. and Rahilly, M. (1991) Non-Epithelial Cellular Components in Eccrine Spiradenoma: A histological and Immunohistochemical Study of 20 Cases. Histopathology, 18, 155-160.
[2] Eckert, F., Betke, M., Schmoeckel, C., Neuweiler, J. and Schmid, U. (1992) Myoepithelial Differentiation in Benign Sweat Gland Tumors. Demonstrated by a Monoclonal Antibody to Alpha-Smooth Muscle Actin. Journal of Cutaneous Pathology, 19, 294-301.
[3] Jitsukawa, K., Sucki, H., Sato, S. and Anzai, T. (1987) Eccrine Spiradenoma: An Electron Microscopic Study. American Journal of Dermatopathology, 9, 99-108
[4] Hey, A., Grouls, V. and Rockelein, G. (1988) Vascular Eccrine Giant Spiradenoma—A Case Report with Histology and Immunohistology of a Rare Variant of Benign Sweat Gland Tumors. Zeitschrift für Hautkrankheiten, 63, 444-447.
[5] Senol, M., Ozcan, A., Sasmaz, S., Ozen, S. and Ciralik, H. (1998) Giant Vascular Eccrine Spiradenoma. International Journal of Dermatology, 37, 221-223.
[6] Ko, J.Y., Lee, C.W., Moon, S.H., Song, K.W. and Park, C.K. (2006) Giant Vascular Eccrine Spiradenoma: Report of a Case with Immunohistochemical Study. Journal of Korean Medical Science, 21, 172-176.
[7] Yamakoshi, T., Makino, T., Watanabe, H., Furuichi, M., Matsui, K. and Shimizu, T. (2009) A Case of Giant Vascular Eccrine Spiradenoma with Unusual Clinical Features. Clinical and Experimental Dermatology, 34, e250-e251.
[8] Kim, M.H., Cho, E., Lee, J.D. and Cho, S.H. (2011) Giant Vascular Eccrine Spiradenoma. Annals of Dermatology, 23, 197-200.
[9] Hatano, A., Kobayashi, T., Fukuzumi, S., Shirakashi, Y., Nishimura, C., Gomi, H., Saiga, H. and Hayakawa, K. (2013) Giant Vascular Eccrine Spiradenoma Mimicking Calcifying Epithelioma. The Journal of Dermatology, 40, 853-854.

Copyright © 2022 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.