Biodegradable Chitosan/Multiwalled Carbon Nanotube Composite for Bone Tissue Engineering

DOI: 10.4236/jbnb.2013.42025   PDF   HTML   XML   5,161 Downloads   7,899 Views   Citations


In this work the influence of multiwalled carbon nanotubes (MWCNT) on mechanical properties was evaluated also the osteoinduction mechanism in Chitosan/MWCNT composite is reported. The morphology and the mechanical properties of the scaffolds were controlled by varying solvent ratios, quenching temperatures and carbon nanotubes concentration. In vitro cell culture of Sprague-Dawley rat’s osteoblasts was used to evaluate the phenotype expression of cells in the scaffolds. The presence of MWCNT in a chitosan matrix improving its mechanical properties and sustain osteoblast growth and differentiation that represent a potential application of the Chitosan/MWCNT as biomaterial for bone tissue engineering.

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I. Olivas-Armendariz, S. Martel-Estrada, M. Mendoza-Duarte, F. Jiménez-Vega, P. García-Casillas and C. Martínez-Pérez, "Biodegradable Chitosan/Multiwalled Carbon Nanotube Composite for Bone Tissue Engineering," Journal of Biomaterials and Nanobiotechnology, Vol. 4 No. 2, 2013, pp. 204-211. doi: 10.4236/jbnb.2013.42025.

Conflicts of Interest

The authors declare no conflicts of interest.


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