How to manage the cenozioc employees to maximize the value of their human capital has always been a problem that plagues the practice world. However, the research on the relationship between the psychological contract and job satisfaction of the cenozioc employees is still scarce. This study examines the relationship between the psychological contract and job satisfaction of the cenozioc employees based on 142 valid data collected through structured questionnaire survey. The empirical results show that the cenozioc employees’ job return satisfaction has positive correlation with the normative responsibility of organization, interpersonal responsibility of organization, developmental responsibility of organization, normative responsibility and developmental responsibility of employee, and has negative correlation with the interpersonal responsibility of employee. The cenozioc employees’ job content satisfaction is positively correlated with the developmental responsibility of organization, normative responsibility and developmental responsibility of employee. The cenozioc employees’ job relationship satisfaction is positively correlated with the interpersonal responsibility of organization and developmental responsibility of employee. The research conclusion has be in favor of the complete understanding of the theory of psychological contract and improvement of job satisfaction of the cenozioc employees from the perspective of psychological contract.