Author(s)

Fathallaah Bazi¹, Bahija Mounir², Mohammed Hamza¹, Said Sebti³

¹Laboratoire de Chimie Analytique et physicochimie des Matériaux, Université Hassan II, Faculté des Sciences Ben M’Sik, Casablanca, Morocco.
²Laboratoire Matériaux, Substances Naturelles, Environnement & Modélisation (LMSNEM), Université Sidi Mohamed Ben Abdellah Fes, Faculté Polydisciplinaire, Taza, Morocco.
³Laboratoire de Chimie Physique Catalyse et Environnement, Université Hassan II, Faculté des Sciences Ben M’Sik, Casablanca, Morocco.

An efficient and clean preparation of acylals from aromatic aldehydes in the presence of synthetic phosphates (flourapatite and hydroxyapatite doped with ZnCl2 and ZnBr2) and acetic anhydride was achieved easily in high yields (86% - 97%) at room temperature under solvent-free conditions. Deprotection of the resulting acylals has also been attained by using the same catalysts under microwave irradiation. This method consistently has advantage of excellent yields (82% - 96%) and a short reaction time (3 - 4 min).

Synthetic Phosphates, Clean Process, Acylals, Protection, Deprotection

Bazi, F. , Mounir, B. , Hamza, M. and Sebti, S. (2018) A Mild and Efficient Method for the Synthesis of Acylals from Aromatic Aldehydes and Their Deprotections Catalyzed by Synthetic Phosphates under Solvent-Free Conditions. Green and Sustainable Chemistry, 8, 334-344. doi: 10.4236/gsc.2018.84023.