As the potential power of social economic development, the importance of startups has attracted more and more attention from academia. The service supply chain, led by the service integrator, can help the startups to improve the performance of the enterprise, achieve better supply chain integration, and go through their “infancy” period successfully. However, the research about the factors that influence the integration of service supply chain and how these factors affect the supply chain integration of startups remains to be explored. Based on the practical problems and theoretical research status above, this study constructs a theoretical hypothesis model of the relationship between interaction, supply chain finance and supply chain integration, and we take the survey data of 65 startups in Pearl River Delta of China as samples and use hierarchical regression analysis to carry out hypothesis testing. The result shows that, from the perspective of startups, interaction has a positive impact on supplier integration, internal integration and customer integration, and supply chain finance has a positive impact on internal integration. The main significance of this study is to make up for the vacancy on this part of the academic community in the service supply chain, and help provide some reference basis for start-up enterprises’ supply chain integration.