The Uses of Cyclopentanone for the Synthesis of Biologically Active Pyran, Pyridine and Thiophene Derivatives - Open Access Library Journal

OALibJ > Vol.3 No.3, March 2016

Open Access Library Journal

Volume 3, Issue 3 (March 2016)

ISSN Print: 2333-9705 ISSN Online: 2333-9721

Google-based Impact Factor: 0.73 Citations

The Uses of Cyclopentanone for the Synthesis of Biologically Active Pyran, Pyridine and Thiophene Derivatives ()

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DOI: 10.4236/oalib.1102532 1,649 Downloads 3,894 Views Citations

Author(s)

Eman M. Samir

Affiliation(s)

National Organization for Drug Control & Research, Cairo, Egypt.

ABSTRACT

In the recent work, a series of novel pyran and pyridine and thiophene derivatives were designed and synthesized starting from 2-benzylidenecyclopentanone. The reactivity of these derivatives towards different chemical reagent was studied. The antitumor evaluations of the newly synthesized products were measured and the results showed that some of the synthesized products showed high cytotoxicity.

KEYWORDS

Cyclopentanone, Pyran, Pyridine, Pyrimidine

Share and Cite:

Samir, E. (2016) The Uses of Cyclopentanone for the Synthesis of Biologically Active Pyran, Pyridine and Thiophene Derivatives. Open Access Library Journal, 3, 1-11. doi: 10.4236/oalib.1102532.

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