Author(s)

Sabrina Macaire¹, Alexandre Catrain¹, Stéphane Tortel¹, Jean-Christophe Joly¹, Sébastien Girard^2,3, Pierre Bonnet^2,3*, Alain Vian⁴

¹CEA, DAM, Gramat, France.
²Institut Pascal, Université Blaise Pascal, Clermont-Ferrand, France.
³CNRS, UMR 6602, Aubière, France.
⁴ARCH-E. Université d’Angers, UMR 1345 IRHS, Angers, France.

Ultrawideband electromagnetic pulses with high amplitude and short duration are reported to affect several aspects of cell physiology. They are usually delivered to the living material through electrodes in small dedicated chambers. Here we showed, using a totally different experimental setup, that radiated EM pulses illuminating the living material through a specialized antenna (without any direct contact) are able to trigger a rapid release of ATP in cultured murine cells that was concomitant with a drop of intracellular AEC. Despite this rapid and strong response, we found that cell viability and clonogenicity were only slightly affected by the EMF exposure.

Radiated Electromagnetic Pulses, Koshelev Antenna, eATP, Cell Viability

Macaire, S. , Catrain, A. , Tortel, S. , Joly, J. , Girard, S. , Bonnet, P. and Vian, A. (2015) Radiated Ultrashort High-Power Electromagnetic Pulses Induce ATP Release in B16F10 Murine Melanoma Cells. Journal of Electromagnetic Analysis and Applications, 7, 66-74. doi: 10.4236/jemaa.2015.73008.