Tibial fractures are one of the most frequent bone fractures caused by accidents or falls because of the tibia’s slender shape. In the tibial fractures close to the joint surface, a plate and screws may be the ideal method of fixation. While using the plate and the screws the estimation of the stress on the plate and screw gains importance before beginning the treatment. In this study, it is aimed to conduct a numerical simulation which uses finite element methodology, to estimate the von Mises stress subjected to the plate and screw which is used in tibia fracture treatment. A titanium plate and 4 screws on it are used for treatment of the fracture. The fracture angle varies as 0°, 15°, 30°, and 45°. The compressive force affected on the plate is estimated to be 750 N. Moreover, the bone is simulated 3D, by using commercial software, ANSYS Structural.