Pea Hull Fiber Improves Bowel Regularity in Both a Healthy and Constipated Rat Model ()
ABSTRACT
Constipation is an area of concern in people’s health. Consequently,
health care practitioners recommend lifestyle changes including increasing
fiber intake and exercise. This study examined the effect of pea hull fiber
(PHF) on loperamide-induced constipation in rats. The rats were fed either a
vehicle diet or a diet enriched with PHF. The groups were divided into either a
saline or loperamide injection to induce sub-acute constipation. Fecal Pellet
Output (FPO) was measured for 3 days. In the saline-treated rats, PHF increased
wet and dry fecal weights on day 1 and 2, and increased FPO on day 2 compared
to the saline-treated rats on the vehicle diet. In the loperamide model, PHF increased FPO, had higher wet and dry fecal weights
on day 1 compared to the loperamide-treated
vehicle diet rats. Addition of PHF into the diet may help improve
intestinal transit in a loperamide-induced constipation rat model.
Share and Cite:
Marcotorchino, J. , Roux, J. , Bariohay, B. , Guerin-Deremaux, L. and Thabuis, C. (2021) Pea Hull Fiber Improves Bowel Regularity in Both a Healthy and Constipated Rat Model.
Food and Nutrition Sciences,
12, 950-961. doi:
10.4236/fns.2021.1210070.
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