Dr. Abdul Rouf Dar

Department of Chemistry,

University of Florida (UF), Gainesville,

Florida, USA

Email: roufdr99@gmail.com

Qualifications

2013 Ph.D, Guru Nanak Dev University, Amritsar, India, Organic chemistry

2005 M.Sc, University of Kashmir, India, Chemistry

Publications (Selected)

1. Ow MC, Nishiguchi MA, Dar AR, Butcher RA and Hall SE (2024), RNAi-dependent expression of sperm genes in ADL chemosensory neurons is required for olfactory responses in Caenorhabditis elegans. Front. Mol. Biosci. 11:1396587. doi: 10.3389/fmolb.2024.1396587

2. Wu, T., Ge, M., Wu, M. et al. Pathogenic bacteria modulate pheromone response to promote mating. Nature 613, 324–331 (2023). https://doi.org/10.1038/s41586-022-05561-9

3. Tatsuhiro Shimizu, Kayoko Sugiura, Yoshiki Sakai, Abdul R. Dar, Rebecca A. Butcher, Kunihiro Matsumoto, Naoki Hisamoto. Chemical Signaling Regulates Axon Regeneration via the GPCR–Gqα Pathway in Caenorhabditis elegans. Journal of Neuroscience 2 February 2022, 42 (5) 720-730; DOI: 10.1523/JNEUROSCI.0929-21.2021

4. Jadiel A. Wasson et al. ,Neuronal control of maternal provisioning in response to social cues.Sci. Adv.7,eabf8782(2021).DOI:10.1126/sciadv.abf8782

Park J, Oh H, Kim D-Y, Cheon Y, Park Y-J, Hwang H, et al. (2021) CREB mediates the C. elegans dauer polyphenism through direct and cell-autonomous regulation of TGF-β expression. PLoS Genet 17(7): e1009678. https://doi.org/10.1371/journal.pgen.1009678

5. Susan E. Mango and group, Abdul Rouf Dar, Rebecca Butcher. Neuronal control of maternal provisioning in response to social cues. Nature, 2020, Ref: 2020-09-17271.

6. JiSoo Park; Hyekyoung Oh; Yeon-Ji Park; Abdul Rouf Dar; Rebecca A Butcher; Piali Sengupta; Daewon Kim; Kyuhyung Kim. CREB mediates the C. elegans dauer polyphenism through direct and cell-autonomous regulation of TGF-b expression, PNAS, 2020, Ref: MS#2020-19874. 3. N. Faghih; S. Bhar; Y. Zhou; Abdul Rouf Dar; K. Mai; L. Bailey; K. Basso; R. Butcher. A large family of enzymes responsible for the modular architecture of nematode pheromones. JACS, 2020, 142, 32, 13645.

7. T. Wu, F. Duan, W. Yang, He Liu, A. Caballero, D. Andrea Fernandes, Abdul Rouf Dar, R. A. Butcher, and Yun Zhang. Pheromones Modulate Learning by

Regulating the Balanced Signals of Two Insulin-like Peptide " Neuron, 2019, 104, 1095.

8. J. Park, W. Choi, Abdul Rouf Dar, R. A. Butcher, and K. Kim. Neuropeptide Signaling Regulates Pheromone-Mediated Gene Expression of a Chemoreceptor Gene in C. elegans. Molecules and cells, 2018; 31;42(1): 28-35.

9. Abdul Rouf, E. Şahin, C. Tanyeli..Divergent synthesis of polysubstituted isoxazoles, isoxazoline-N-oxides, and dihydroisoxazoles by one-pot cascade reaction. Tetrahedron 2017, 73, 331.

10. M. Ahmad, M. Aga, J. Bhat, B. Kumar, Abdul Rouf, D. Mondhe, M. Mintoo, G. Mahajan, B. Shah, Subhash Taneja, Abid Hamid. Exploring 3-hydroxypyrrolidine moiety of l-Vasicine as cap group in the design of antitumor histone deacetylase inhibitors. J. Med. Chem, 2017, 60 (8), 3484.

11. Mushtaq A. Aga, Sheikh Rayees, Abdul Rouf,* Brijesh Kumar, Gurdarshan Singh, Subhash C. Taneja. Synthesis of Ofornine mimics from natural source l-Vasicine as anti-hypertensive agents. Bioorg. Med. Chem, 2017, 25, 4, 1440.

12. Carlos Kleber Z. Andrade, Abdul Rouf. Applying green processes and techniques to simplify reaction work-ups. Tetrahedron 2016, 72, 47, 7375-7391.

13. Abdul Rouf, Cihangir Tanyeli. Squaramide based organocatalysts in organic transformations. Curr. Org. Chem, 2016, 20, 28, 2996-3013.

14. Tabasum Ismail, S. Shafi, S. Singh, T. Sidiq, Abdul Rouf, M. Yadav. P. Singh, M. S. Alam, K. Sharma. H. M. Sampath Kumar. Synthesis and immunopotentiating activity of novel isoxazoline functionalized coumarins. Eur. J. Med. Chem. 2016, 123, 10, 90.

15. Abdul Rouf, Cihangir Tanyeli. Bioactive thiazole and benzothiazole derivatives. Eur. J. Med. Chem. 2015, 97, 911.

16. Abdul Rouf,* M. A. Aga, B. Kumar, S. C. Taneja. (R)-2,3-Cyclohexylideneglyceraldehyde, a chiral pool synthon for the synthesis of 2-azido-1,3-diols. Helv. Chim. Acta 2015, 98, 823.

17. Abdul Rouf,* Subhash. C. Taneja. Synthesis of single-enantiomer bioactive molecules: a brief overview. Chirality 2014, 26, 63.

18. B. Kumar, M. A. Aga, Abdul Rouf, B. A. Shah, S. C. Taneja. Common Precursor Strategy for the Synthesis of Bestatin, Amprenavir intermediate and Syn-4-hydroxy-5-phenyl-γ-lactam. RSC Adv. 2014, 4, 17206.

19. B. Kumar, M. A. Aga, Abdul. Rouf, B. A. Shah, S. C. Taneja. Tetrahydropyranyl ether (THPE) formation in hydroxyl group protection and conversion to other useful functionalities. RSC Adv. 2014, 4, 21121.

20. M. A. Aga, B. Kumar, Abdul Rouf, B. A. Shah, S. C. Taneja. Vasicine as Tridentate Ligand for Enantioselective Addition of Diethyl Zinc to Aldehydes. Tetrahedron Lett. 2014, 55, 2639.

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