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Creatine HCl and Creatine Monohydrate Improve Strength but Only Creatine HCl Induced Changes on Body Composition in Recreational Weightlifters

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DOI: 10.4236/fns.2015.617167    4,863 Downloads   6,151 Views   Citations

ABSTRACT

Background: Creatine supplementation is a subject that is very well studied. New forms of creatine are suggesting improvements in this supplement performance. Creatine HCl is supposed to have better solubility and absorption than creatine. The aim of this study was to compare the effects of two different doses of creatine HCl with creatine monohydrate on the strength and body composition in recreational weightlifters and to verify the relationship between strength and body composition. Methods: 40 subjects were divided in four groups: Creatine Monohydrate (CMG) 5 g/daily; Creatine HCl-1 (HCl-1) 5 g/daily, Creatine HCl-2 (HCl-2) 1.5 g/daily and Control group (CG) = 5 g of resistant starch/daily. All groups performed a resistance training program during 4 weeks. Body composition and strength were evaluated pre and post intervention. Results: The 1 RM at the Leg press was increased significantly in all groups (CMG: pre = 264.4 ± 83.8 × post = 298.1 ± 90.9; HCl-1: pre = 295.0 ± 88.3 × post = 338.3 ± 86.8 and HCl-2: pre = 274.3 ± 57.1 × post = 305.7 ± 59.4; p< 0.05), Bench press 1 RM was increased significantly only in HCl-2 (pre = 72.4 ± 25.7 × post = 76.0 ± 25.0; p = 0.003), however, there was no statistically significant difference between groups. Fatmass was significantly decreased in HCl-1 (pre = 14.5 ± 8.0 × post = 13.3 ± 8.3; p = 0.034) and HCl-2 (pre = 13.8 ± 5.8 × post = 12.7 ± 5.6; p = 0.005) but fat-free mass was increased only in HCl-1 (pre = 52.2 ± 8.9 × post = 53.8 ± 8.9; p = 0.031), with no differences between groups again. We observed strong correlations between upper limb strength and fat mass (r = 0.93, p < 0.05), and between lower limb strength and FFM (r = 0.93, p < 0.05) only in HCl-1 group. Conclusions: We concluded that creatine HCl and creatine Monohydrate improve performance but only creatine HCl induces changes on body composition in recreational weightlifters with differences between creatine HCl doses.

Conflicts of Interest

The authors declare no conflicts of interest.

Cite this paper

França, E. , Avelar, B. , Yoshioka, C. , Santana, J. , Madureira, D. , Rocha, L. , Zocoler, C. , Rossi, F. , Lira, F. , Rodrigues, B. and Caperuto, É. (2015) Creatine HCl and Creatine Monohydrate Improve Strength but Only Creatine HCl Induced Changes on Body Composition in Recreational Weightlifters. Food and Nutrition Sciences, 6, 1624-1630. doi: 10.4236/fns.2015.617167.

References

[1] Terjung, R.L., Clarkson, P., Eichner, E.R., Greenhaff, P.L., Heel, P.J., Israel, R.G., Kraemer, W.J., Meyer, R., Ariet, L.L., Tarnopolsky, M.A., Wagenmakers, A.J. and Williams, M.H. (2000) American College of orts Medicine Roundtable: The Physiological and Health Effects of Oral Creatine Supplementation. Medicine & Science in Sports & Exercise, 32, 706-717.
[2] Lanhers, C., Pereira, B., Naughton, G., Trousselard, M., Lesage, F.X. and Dutheil, F. (2015) Creatine Supplementation and Lower Limb Strength Performance: A Systematic Review and Meta-Analyses. Sports Medicine, 45, 1285-1294.
http://dx.doi.org/10.1007/s40279-015-0337-4
[3] Groeneveld, G.J., Beijer, C., Veldink, J.H., Kalmijn, S., Wokke, J.H. and Vandenberg, L.H. (2005) Few Adverse Effects of Long-Term Creatine Supplementation in a Placebo-Controlled Trial. International Journal of Sports Medicine, 26, 307-313.
[4] Benzi, G. (2000) Is There a Rationale for the Use of Creatine Either as Nutritional Supplementation or Drug Administration in Humans Participating in a ort? Pharmacological Research, 41, 255-264.
http://dx.doi.org/10.1006/phrs.1999.0618
[5] Graham, A.S. and Hatton, R.C. (1999) Creatine: A Review of Efficacy and Safety. Journal of the American Pharmaceutical Association (Wash), 39, 803-810, quiz 875-877.
[6] Ostojic, S.M. and Ahmetovic, Z. (2008) Gastrointestinal Distress after Creatine Supplementation in Athletes: Are Side Effects Dose Dependent? Research in Sports Medicine, 16, 15-22.
http://dx.doi.org/10.1080/15438620701693280
[7] Dash, A.K., Miller, D.W., Huai-Yan, H., Carnazzo, J. and Stout, J.R. (2001) Evaluation of Creatine Transport Using Caco-2 Monolayers as an in Vitro Model for Intestinal Absorption. Journal of Pharmaceutical Sciences, 90, 1593-1598.
http://dx.doi.org/10.1002/jps.1109
[8] Gufford, B.T., Sriraghavan, K., Miller, N.J., Miller, D.W., Gu, X., Vennerstrom, J.L. and Robinson, D. (2010) Physicochemical Characterization of Creatine N-Methylguanidinium Salts. Journal of Dietary Supplements, 7, 240-252.
http://dx.doi.org/10.3109/19390211.2010.491507
[9] Gufford, B.T., Ezell, E.L., Robinson, D.H., Miller, D.W., Miller, N.J., Gu, X. and Vennerstrom, J.L. (2013) Dependent Stability of Creatine Ethyl Ester: Relevance to Oral Absorption. Journal of Dietary Supplements, 10, 241-251.
http://dx.doi.org/10.3109/19390211.2013.822453
[10] Lohman, T.G. (1986) Applicability of Body Composition Techniques and Constants for Children and Youths. Exercise & Sport Sciences Reviews, 14, 325-357.
http://dx.doi.org/10.1249/00003677-198600140-00014
[11] Jackson, A.S. and Pollock, M.L. (1978) Generalized Equations for Predicting Body Density of Men. British Journal of Nutrition, 91, 161-168.
http://dx.doi.org/10.1079/bjn19780152
[12] Brown, L.E. and Weir, J.P. (2003) Recomendação de procedimentos da Sociedade Americana de Fisiologia do Exercício (ASEP) I: Avaliação precisa da força e potência muscular. Revista Brasileira de Ciência e Movimento, Brasília, 11, 95-110.
[13] Hultman, E., Söderlund, K., Timmons, J.A., Cederblad, G. and Greenhaff, P.L. (1996) Muscle Creatine Loading in Men. Journal of Applied Physiology, 81, 232-237.
[14] Francaux, M. and Poortmans, J.R. (1999) Effects of Training and Creatine Supplement on Muscle Strength and Body Mass. European Journal of Applied Physiology and Occupational Physiology, 80, 165-168.
http://dx.doi.org/10.1007/s004210050575
[15] Powers, M.E., Arnold, B.L., Weltman, A.L., Perrin, D.H., Mistry, D., Kahler, D.M., Kraemer, W. and Volek, J. (2003) Creatine Supplementation Increases Total Body Water Without Altering Fluid Distribution. Journal of Athletic Training, 38, 44-50.
[16] Branch, J.D. (2003) Effect of Creatine Supplementation on Body Composition and Performance: A Meta-Analysis. International Journal of Sport Nutrition and Exercise Metabolism, 13, 198-226.
[17] Bembem MG, Lamont HS. Creatine supplementation and exercise performance: recent findings. orts Med. 2005; 35(2), 107-125.
[18] Devries, M.C. and Phillips, S.M. (2014) Creatine Supplementation during Resistance Training in Older Adults—A Meta-Analysis. Medicine & Science in Sports & Exercise, 46, 1194-1203.
http://dx.doi.org/10.1249/MSS.0000000000000220
[19] Kilduff, L.P., Lewis, S., Kingsley, M.I., Owen, N.J. and Dietzig, R.E. (2007) Reliability and Detecting Change Following Short-Term Creatine Supplementation: Comparison of Two-Component Body Composition Methods. The Journal of Strength & Conditioning Research, 21, 378-384.
http://dx.doi.org/10.1519/00124278-200705000-00015
[20] Moon, J. (2013) Body Composition in Athletes and Sports Nutrition: An Examination of the Bioimpedance Analysis Technique. European Journal of Clinical Nutrition, 67, S54-S59.
http://dx.doi.org/10.1038/ejcn.2012.165
[21] Larson-Meyer, D.E., Hunter, G.R., Trowbridge, C.A., Turk, J.C., Ernest, J.M., Torman, S.L. and Harbin, P.A. (2000) The Effect of Creatine Supplementation on Muscle Strength and Body Composition during Off-Season Training in Female Soccer Players. The Journal of Strength & Conditioning Research, 14, 434-442.
[22] Sundgot-Borgen, J. and Garthe, I. (2011) Elite Athletes in Aesthetic and Olympic Weight-Class Sports and the Challenge of Body Weight and Body Compositions. Journal of Sports Sciences, 29, S101-S114.
[23] Tang, F.C., Chan, C.C. and Kuo, P.L. (2013) Contribution of Creatine to Protein Homeostasis in Athletes after Endurance and Sprint Running. European Journal of Nutrition, 53, 61-71.

  
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