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has been cited by the following article:

• TITLE: Sinogenic Subdural Empyema in a Ten-Year-Old Boy with Sickle Cell Anemia

  AUTHORS: Ulf Nestler, Daniel Memia-Zolo, Nidal Salloum, Mehdi Mejdoubi, François Lengelle, Raoul Santiago, William Cécile, Remus Stegaru, Norbert Manzo

  KEYWORDS: Nasal Sinusitis; Sickle Cell Anemia; Streptococcus Pneumoniae; Subdural Empyema

  JOURNAL NAME: Open Journal of Modern Neurosurgery, Vol.3 No.4, October 15, 2013

  ABSTRACT: Objective: Sinogenic subdural empyema remains a neurosurgical emergency, even in the antibiotic era. Sickle cell disease is one of the most frequent hereditary diseases, with an incidence of around 4 in 1000 newborns, which necessitates special considerations before a neurosurgical intervention. Case Description: The case of a 10-year-old boy with sickle cell disease type HbSC is reported, who presented with meningitis about ten days after a nasal sinusitis. CT and MRI showed subdural empyema and immediate intravenous antibiotic treatment was started. The patient received partial exchange transfusion. Craniotomy allowed evacuation of empyema and repairment of a frontobasal dural defect. Endoscopic evacuation of the paranasal sinuses was done in the same anesthesia. After initial good recovery, the patient developed right sided paresis with epileptic seizures a few days later. CT scan revealed three distant empyema recurrencies which were evacuated in a second neurosurgical intervention. The child recovered without neurologic deficit, and control MRI examinations three and twelve months after surgery found frontal and parietal dural thickening as sequelae. Conclusion: Urgent neurosurgical interventions in the presence of sickle cell anemia require special anesthesiologic preparations. An immediate, multidisciplinary approach can lead to a good outcome in these life-threatening situations.