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has been cited by the following article:

• TITLE: Research of Quality Standards for Stachydrine Hydrochloride in Chinese Medicine TJF Granule

  AUTHORS: Yao Lu, Wei Yu, Pingniang Shen, T. J. Khoo, C. Wiart

  KEYWORDS: TJF Granule; Quality Standards; Traditional Chinese Medicine; Evaporative Light Scattering Detector (ELSD); High-Performance Liquid Chromatographic (HPLC) Method; Stachydrine Hydrochloride; Pharmaceutical Analysis; Determination

  JOURNAL NAME: Pharmacology & Pharmacy, Vol.4 No.3, May 31, 2013

  ABSTRACT: A high-performance liquid chromatographic method was applied to the determination of stachydrine hydrochloride concentration in TJF granule (Chinese name: Tiao-Jing-Fang), using a mobile phase of methanol-acetonitrile (50:50, v/v) by the Agilent Kromasi NH2 column (250 mm × 4.6 mm, 5 μm, S/N: 22N25110). Detection wavelength was 201 nm. The result revealed good linearity of stachydrine hydrochloride and was obtained within the range of 0.20 - 1.98 μg/mL (R = 0.9995). The average recovery was 97.01%; the relative standard deviation (RSD) was 0.19%. To the best of our knowledge, this is the first report dedicated to the determination of stachydrine hydrochloride by the evaporative light scattering detector-high-performance liquid chromatographic (ELSD-HPLC) method.