TITLE:
n-Dodecylbenzene Sulfonic Acid (DBSA) as a Novel Brønsted Acid Catalyst for the Synthesis of Bis(indolyl)methanes and Bis(4-hydroxycoumarin-3-yl)methanes in Water
AUTHORS:
Balu Pawar, Vinod Shinde, Atul Chaskar
KEYWORDS:
n-Dodecylbenzene Sulfonic Acid (DBSA); Indole; Aldehyde; Bis(indolyl)methane; Bis(4-hydroxycoumarin-3-yl)methanes
JOURNAL NAME:
Green and Sustainable Chemistry,
Vol.3 No.2,
May
27,
2013
ABSTRACT: n-Dodecylbenzene sulfonic acid (DBSA) as a novel, biodegradable, and efficient Br?nsted acid catalyst used for the reaction of indoles/4-hydroxy coumarin with aldehydes to obtain a bis(indolyl)methanes/bis(4-hydroxycoumarin-3-yl)methanes, respectively. The catalyst exhibited remarkable activity, and tolerated a wide variety of functional groups providing the desired bis(indolyl)methanes and bis(4-hydroxycoumarin-3-yl)methanes in good to excellent yield (70%-96%) in water.