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C. Vitali, S. Bombardieri, R. Jonsson, H. M. Moutsopoulos, E. L. Alexander, S. E. Carsons, T. E. Daniels, P. C. Fox, R. I. Fox, S. S. Kassan, S. R. Pillemer, N. Talal, M. H. Weisman, European Study Group on Classification Criteria for Sjogren’s Syndrome, “Classification Criteria for Sjogren’s Syndrome: A Revisal of the European Criteria Proposed by the American-European Consensus Group,” Annals of Rheumatic Diseases, Vol. 61, No. 6, 2002, pp. 554-558. doi:10.1136/ard.61.6.554
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TITLE:
Kikuchi-Fujimoto Disease in Patients with Sjögren’s Syndrome
AUTHORS:
Lida Radfar, Mehdi Radfar, Kathy L. Moser, Robert Hal Scofield
KEYWORDS:
Sjögren’s Syndrome; Kikuchi-Fujimoto Disease
JOURNAL NAME:
Open Journal of Pathology,
Vol.3 No.1,
January
28,
2013
ABSTRACT:
Sjogren’s syndrome is a chronic autoimmune exocrinopathy associated with dry eyes and dry mouth as major clinical manifestations. It is characterized by lymphocytic infiltration of lacrimal and salivary glands and autoantibody production, especially anti-Ro (or SSA) and anti-La (or SSB). Lymphoproliferative disorders are a feature of Sjogren’s syndrome, and can be considered an extraglandular manifestation of the disease. Kikuchi-Fujimoto disease or histiocytic necrotizing lymphadenitis is a rare form of lymphadenitis. It is reported more often in young adult women with localized lymphadenopathy (usually cervical), fever, rashes, and leukopenia. It is a self-limiting disease with resolution within 1 - 4 months in almost all patients. Sjogren’s syndrome has been reported in patients with other systemic diseases including SLE and lymphomas. Here we present a patient with Kikuchi-Fujimoto disease who developed Sjogren’s Syndrome 8 years after her diagnosis of Kikuchi-Fujimoto disease.