TITLE:
Efficacy and Safety of Avillon Diamond Dermal Fillers in Facial Rejuvenation
AUTHORS:
Zekayi Kutlubay, Turana Mammadova, Bilal Doğan, Meral Çetin
KEYWORDS:
Facial Rejuvenation, Hyaluronic Acid Fillers, Dermal Fillers, Volume Restoration, Lifting Effect, Midface Contouring, Wrinkle Correction
JOURNAL NAME:
Journal of Cosmetics, Dermatological Sciences and Applications,
Vol.16 No.3,
September
2,
2026
ABSTRACT: Background: Advances in medicine and increased life expectancy have intensified the demand for youthful facial appearance, driving a rise in aesthetic procedures addressing age-related wrinkles, folds, laxity, and sagging. Facial aging involves not only soft tissue but also skeletal volume loss, altering midface, perioral, and lip contours. This study evaluates the efficacy and safety of Avillon Diamond dermal fillers (Deep, Fine, Lips) for age-related facial volume and elasticity loss over six months. Patients/Methods: This multi-center, prospective, non-randomized clinical trial included 193 healthy female patients (>21 years) without prior minimally invasive aesthetic treatments. Avillon Diamond products were injected into various facial regions. Efficacy and safety were assessed at predefined intervals using the Medicis Midface Volume Scale (MMVS), Wrinkle Severity Rating Scale (WSRS), and Global Aesthetic Improvement Scale (GAIS). Results: Treatment significantly improved facial volume and contour across all facial areas. In the Deep group, severe volume loss decreased from 47.5% at baseline to 8.2% at month six. In the Fine group, mild-moderate volume loss persisted in 76% of patients at six months. In the Lips group, thin lips (55% at baseline) improved to full lip volume in 71.7% at day 14% and 56.7% at month six. Minimal, transient adverse events were observed. Patient satisfaction remained high, with sustained aesthetic outcomes over six months. Conclusions: Avillon Diamond hyaluronic acid fillers provide effective and safe facial rejuvenation with durable lifting and volumizing effects. High patient and physician satisfaction and a favorable safety profile support their use in aesthetic dermatology. Additional treatments may enhance long-term outcomes.