Ohno, A., Ano, T. and Shoda, M. (1996) Use of soybean curd residue, okara, for the solid state substrate in the production of a lipopeptide antibiotic, iturin A, by Bacillus subtilis NB22. Process Biochemistry, 31, 801-806. doi:10.1016/S0032-9592(96)00034-9

has been cited by the following article:

• TITLE: Production of iturin A through glass column reactor (GCR) from soybean curd residue (okara) by Bacillus subtilis RB14-CS under solid state fermentation (SSF)

  AUTHORS: Abdul Wahab Khan, Umme Salma Zohora, Mohammad Shahedur Rahman, Masahiro Okanami, Takashi Ano

  KEYWORDS: Solid State Fermentation; Okara; Iturin A; Glass Column Reactor

  JOURNAL NAME: Advances in Bioscience and Biotechnology, Vol.3 No.2, April 18, 2012

  ABSTRACT: The present study was conducted with an aim to scale up the production of iturin A using soybean curd residue (okara). Iturin A was produced by indigenous bacterial strain Bacillus subtilis RB14-CS through glass column reactor (GCR) under solid state fermentation (SSF) was characterized. The enhanced iturin A production was observed with respect to enhanced substrate bed height when SSF was conducted in Erlenmeyer flask. To check the effect of substrate bed height on iturin A production under SSF of okara, GCR was introduced. Substrate bed height of 15 cm was suitable for iturin A production which was about 2700 mg/kg wet substrate. The observed iturin A production by the aerobic bacteria Bacillus subtilis in nearly anaerobic condition in such high substrate bed for SSF is a wonderful finding for development of SSF system in future.