TITLE:
Impact of COVID-19 Infection on hospitalized Patients with Cardiovascular Diseases at the Regional Hospital Center of Saint-Louis, Senegal
AUTHORS:
Serigne Mor Beye, Alassane Dieye, Mba El Hadji Bambo Diakhaby, Myriam Djedjelaife Aline Okoko, Moustapha Diedhiou, Ndiambé Sarr, Ibrahima Louis Martin Dieng, Seynabou Lo, Ndeye Mery Dia-Badiane
KEYWORDS:
COVID-19, Cardiovascular Diseases, Risk Factors, Senegal
JOURNAL NAME:
World Journal of Cardiovascular Diseases,
Vol.15 No.11,
November
25,
2025
ABSTRACT: Background: Patients with comorbidities cardiovascular diseases (CVD) present an increased risk of severe COVID-19 forms. This study aims to describe the characteristics and prognostic factors of cardiovascular patients hospitalized for COVID-19 in Saint Louis, Senegal. Methods: A retrospective single-center study was conducted at the Epidemic Treatment Center (ETC) of Saint-Louis Regional Hospital Center (RHC) from March 2020 to December 2021. All adult patients with positive PCR for SARS-CoV-2 and at least one cardiovascular pathology were included. Sociodemographic, clinical, biological, and evolutionary data were analyzed. Results: Among 450 hospitalized patients, 97 (21.6%) met inclusion criteria. Mean age was 59 years (±14.9) with male predominance (55.7%). Hypertension (39.2%) and diabetes (24.7%) were the most frequent comorbidities. Cough (48.5%) and dyspnea (46.4%) were predominant symptoms. Overall case fatality rate was 7.2%. In univariate analysis, advanced age (p = 0.048), severe COVID-19 form (p = 0.009), elevated CRP (p Conclusion: This study confirms the significant burden of cardiovascular risk factors among patients hospitalized for COVID-19 in Senegal. Age and biological markers of inflammation, myocardial injury, and renal dysfunction are key prognostic determinants, emphasizing the need for particular vigilance in this vulnerable population. Early intervention strategies should include systematic monitoring of CRP and troponin levels, close surveillance of renal function, and intensive management protocols for patients with cardiovascular comorbidities presenting with elevated inflammatory markers.