TITLE:
Contraindications of Using Fractional CO2 Laser in the Treatment of Aesthetic Disorders: A Narrative Review
AUTHORS:
Fábio dos Santos Borges, Margarete Diprat Trevisan, Amanda Aguiar Sampaio Ferraz, Giovanna Pontes Pina Vidal, Flavianny Silva Artiaga, Tatiane Coutinho, Nara Gazola, Fabio de Abranches Quintão Neto, Elisa Marchesini, Rodrigo Soliva Jahara
KEYWORDS:
Fractional CO2 Laser, Carbon Dioxide Laser, Contraindications, Aesthetic Medicine
JOURNAL NAME:
Journal of Biosciences and Medicines,
Vol.13 No.9,
September
8,
2025
ABSTRACT: Introduction: Despite its proven efficacy, the use of fractional CO2 laser therapy is not without risks. Several complications and adverse effects may occur following its application. However, it is widely understood that if the procedure’s contraindications are properly observed, such adverse events can be prevented. Therefore, specific contraindications must be carefully evaluated to ensure patient safety and optimal outcomes. Objective: To describe the contraindications regarding the use of fractional CO2 laser techniques applied to the treatment of aesthetic disorders, with the purpose of ensuring a safe and effective procedure, while preventing complications during and after treatment. Methodology: This study is characterized as exploratory research presented through a narrative review, aiming to highlight the need and importance of rigorous patient selection for the treatment of aesthetic and functional disorders using fractional CO2 laser. Results: The most frequently cited contraindications in the reviewed literature include pigmentary disorders and high phototypes, active autoimmune diseases, active inflammatory skin conditions and acne, photosensitivity, pregnancy or breastfeeding, history of keloids or hypertrophic scars, active infections in the treatment area, previous ablative laser treatment in the same area, use of isotretinoin in the past year, and use of anticoagulants. Conclusion: Careful patient selection based on awareness of contraindications and individualized therapeutic planning emerges as the foundation for maximizing the benefits of fractional CO2 laser and minimizing associated risks, thereby ensuring quality and safety for patients seeking this therapeutic resource.