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https://doi.org/10.5530/pj.2015.2.2

has been cited by the following article:

• TITLE: Phytochemical Screening and Therapeutic Effect of Solanum torvum Root Extract on Some Clinical Signs of Malaria Induced in Wistar Rats

  AUTHORS: Justine Wawa Tiekpa, Adrien Mani Kouangbe, Marcelin Armand Konan Kouassi, Sévérin Kouakou Konan, Calixte Bahi

  KEYWORDS: Solanum torvum, Aqueous Extract, Treatment, Clinical Signs, Malaria

  JOURNAL NAME: Journal of Biosciences and Medicines, Vol.13 No.9, September 2, 2025

  ABSTRACT: Background and Objectives: Malaria is very often characterized by fever, pain, and anemia. Its treatment in modern medicine always includes a medication for each symptom, which can sometimes be difficult for patients to take. The aim of this work is to assess the therapeutic potential of Solanum torvum roots aqueous extract for a single treatment of all three malarial symptoms in animal model. Methods: After inducing all the three malarial manifestations in healthy rats, they were treated with doses of S. torvum root extract in comparison to reference molecules for each symptom. The extract’s therapeutic efficacy was indicated by hematological parameters to diagnose anemia, while temperature and number of writhings were used to indicate fever and pain, respectively. Results: The induction of symptoms was characterized by significant increase (p 6/mm3, and significant decrease (p Conclusion: The therapeutic efficacy thus observed supports the use of Solanum torvum in the treatment of malaria symptoms and allows for the development of an effective single treatment for these symptoms.