A. Wube, F. Bucar, C. Hochfellner, M. Blunder, R. Bauer and A. Hüfner, “Synthesis of N-Substituted 2-[(1E)-Al- kenyl]-4-(1H)-Quinolone Derivatives as Antimycobacterial Agents against Non-Tubercular Mycobacteria,” European Journal of Medicinal Chemistry, Vol. 46, No. 6, 2011, pp. 2091-2101. doi:10.1016/j.ejmech.2011.02.062

has been cited by the following article:

• TITLE: Highly Efficient Synthesis of Novel Fluorine Bearing Quinoline-4-carboxylic Acid and the Related Compounds as Amylolytic Agents

  AUTHORS: Mohammed S. T. Makki, Dina A. Bakhotmah, Reda M. Abdel-Rahman

  KEYWORDS: Amylolytic Activity; Amylolytic Agents; Aspergillus fungi; Efficient Synthesis; Fluoroquinoline;Quinoline-4-carboxylic Acids

  JOURNAL NAME: International Journal of Organic Chemistry, Vol.2 No.1, March 15, 2012

  ABSTRACT: Highly efficient syntheses of novel fluorine bearing quinoline-4-carboxylic acids and the related compounds had been achieved from cyclocondensation of 2-amino-5-fluorophenyl glyoxylic acid 1 with benzoyle asetanilides 2 in boiling DMF, to give the target 3. Decarboxylation of 3 produced 6-fluoro-2-phenyl-3-(substituted amino)-keto-quinolines 4, while that reaction underwent refluxing, afforded 7-fluoro-1-(aryl)-3-phenyl-pyrrolo[3,4-c] quinoline-2,9-diones 5. Structure of the products has been established from their elemental and spectral analysis. All targets exhibited a high to moderate activity against some Aspergillus fungi as amylolytic agents.