TITLE:
Pagets Disease of the Breast
AUTHORS:
Nneka A. Sunday-Nweke, Kenneth A. Omoruyi, Ozoemena S. Oboke, Chinyere Duru, Onyeyirichi Otuu, Moses I. Ekuma, Samuel U. Okparaoka, Somadina Ikpeze, Udu C. Udu
KEYWORDS:
Clinical Characteristics, Pathological Features, Treatment Modalities, Mammary Paget’s Disease
JOURNAL NAME:
Advances in Breast Cancer Research,
Vol.14 No.3,
May
26,
2025
ABSTRACT: Background: Paget’s disease of the breast also called mammary Paget’s disease [MPD] was first described by Sir James Paget an English surgeon and a medical pioneer in the 19th century in 1874. In his report, fifteen women with a chronic eczematous disease on the skin of the nipple and the areola also had an associated intra ductal carcinoma of the underlying mammary gland. It is a rare type of cancer that develops in the skin of the nipple, and sometimes the areola, for this reason patients tend to take it less seriously. Conclusion: The treatment for Paget’s disease of the breast typically involves surgery, usually a mastectomy or breast conserving surgery with radiation, and effective chemotherapy or hormone therapy, depending on the underlying cancer’s characteristics.