TITLE:
Epidemiological and Anatomopathological Profile of Breast Cancer at Anoalite Hospital in Mungbere
AUTHORS:
Jean-Faustin Atakuru Gaga, Jeremy Likilo Osundja, Jean-Marie Demupondo Lukangi, Amos Kaghoma Sivulyamwenge, Jean-Didier Bosenge Nguma, Noel Labama Otuli, Gédéon Katenga Bosunga, Jean-Jeannot Jukali Sihalikyolo, Emmanuel Komanda Likwekwe, Antoine Modia O’yandjo
KEYWORDS:
Breast Cancer, Epidemiology, Anatomopathology, Woman, Mungbere
JOURNAL NAME:
Journal of Biosciences and Medicines,
Vol.13 No.4,
April
8,
2025
ABSTRACT: Introduction: Breast cancer is a global threat that mainly affects women. Worldwide, its prevalence in 2020 was 2.3 million cases and its incidence was 58.5 cases per 100,000 inhabitants. This study was conducted with the aim of describing the epidemiological and anatomo-pathological profile of breast cancer at Anoalite Hospital in Mungbere. Materials and Methods: This study was conducted at the Anoalite Hospital in Mungbere, located 138 km from Isiro, in the extreme northeast of the Haut-Uele province. This was a cross-sectional descriptive study with retrospective data collection, spanning from January 1, 2019 to December 31, 2023, i.e. over a period of 5 years. The study population consisted of any patient who visited the hospital during our study period. We used exhaustive sampling. Data collection was retrospective based on documentary technique. Data entry was carried out using Microsoft Office 365 Excel 2024 software and analyzed using Epi-Info CDC version 7.5.2.0 software. Results: The age group between 61 and 70 years was predominated (30%), single patients were the most affected (67.3%) and unemployed patients (66.8%). Most of the patients came from Isiro (27.6%). The paraclinical results showed that 82.0% had BI-RADS 5, while glucose tolerance abnormality was observed in 3.2% of patients. Infiltrating cancer was the most observed in our series (85.3%), among which 94.1% were carriers of the ductal type. On the other hand, among the 14.7% of patients who were carriers of in situ cancer, 53.1% had the ductal type. The majority of our respondents had grade III of SBR with 91.7%; 94.0% were estrogen receptor-positive and all patients had HER2 overexpressed status > 30%. Finally, all our subjects had Ki 67 ≥ 20%. Conclusion: Breast cancer is a real public health problem in our community. Several measures are needed to make early detection more accessible.