TITLE:
Massive Splenic Infarction Following COVID-19 Infection, with Histopathological Observations, and Review of the Literature
AUTHORS:
Yousef Samir Amr, Aseel Qassem Al-Omari, Mousa Husein Saadeh, Samir Sami Amr
KEYWORDS:
COVID-19, Splenic Infarction, Hyper-Coagulability, Thrombosis
JOURNAL NAME:
Open Journal of Pathology,
Vol.15 No.2,
April
1,
2025
ABSTRACT: We report a 63-year-old man who developed massive splenic infarction two months following COVID-19 infection. He presented with high grade fever, weakness, dysuria and chronic productive cough. He was found to have a large splenic infarction involving most of the spleen. We document the course and outcome of his illness, and the histopathological findings of the resected spleen. A discussion of COVID-19 associated hypercoagulability is presented, with a comprehensive review of the literature on splenic infarction associated with COVID-19 infection.