TITLE:
COVID-19 Vaccine Uptake: Prevalence, Health Facility Enablers and Barriers among Adult Tuberculosis Patients across Nairobi County Clinics, Kenya
AUTHORS:
Waqo Boru, George Makalliwa, Caroline Musita
KEYWORDS:
Coronavirus, COVID-19, Enablers, Barriers, Tuberculosis, Vaccine Uptake
JOURNAL NAME:
Journal of Tuberculosis Research,
Vol.13 No.1,
March
21,
2025
ABSTRACT: Patients with tuberculosis (TB) are at increased risk of developing severe forms of novel coronavirus 2019 (COVID-19), and COVID-19 coinfection aggravates active TB progression through immunosuppression. Despite the availability of COVID-19 vaccines to prevent and reduce COVID-19 transmission, COVID-19 vaccine uptake levels remain low worldwide. In Kenya, an African country with high TB prevalence and TB-HIV coinfection, 47% of the population had received the COVID-19 vaccine by 2023. This study determined health-system enablers and barriers to the COVID-19 vaccine among adult TB patients across Nairobi County TB clinics in Kenya. An analytical cross-sectional study was used. Three hundred eighty-eight TB patients from six TB clinics across six sub-counties in Nairobi were recruited. The participants completed the study questionnaire. After confounding for age, employment status perceived COVID-19 susceptibility, and perceived COVID-19 seriousness, health system enablers of COVID-19 vaccine uptake were consistent and positive messaging on COVID-19 (adjusted odds ratio (aOR) = 4.498; 95% CI: 1.953 - 10.36, p