TITLE:
Centrosomes and Not-Coding DNA during the Emergence and Evolution of Bilaterally Symmetric Complex Organs: Computational Models
AUTHORS:
Marco Franco Giulio Regolini
KEYWORDS:
Symmetry, Chirality, Enantiomorphism, Satellite DNA, Tandem Repeats
JOURNAL NAME:
Advances in Bioscience and Biotechnology,
Vol.16 No.2,
February
18,
2025
ABSTRACT: The origin of complex biological symmetric structures has long been a subject of interest and debate. How new sophisticated structures arise, perfectly meshed together, and added to preexisting organs without breaking their anatomy and physiology remains challenging. A mystery is how endless amounts of new bilaterally symmetric organs have arisen in an infinite number of species: bilateral symmetry requires two different pathways for arranging and driving cells in symmetric locations in the left and right halves of the organism. It is unsustainable that two different genetic codes, independent of each other and assembled by chance, have simultaneously arisen for every organ in millions of different species. Many findings have evidenced that DNA tandem repeats and centrosomes are involved in morphogenesis, suggesting they have played a role in the evolution of shapes. This paper introduces computational simulations to test and ascertain whether DNA tandem repeats and centrosomes can manage and accelerate the evolution of complex organs and bilaterally symmetric structures. The present study follows an interdisciplinary perspective that combines biology and computational modeling to understand cellular behavior across species, underlying the similarity between programming and cellular procedures. The integration of programming codes, tandem repeats, centrioles, and centrosomes provides a potential framework for investigating fundamental biological processes.